NSD1 deposits histone H3 lysine 36 dimethylation to pattern non-CG DNA methylation in neurons

During postnatal development the DNA methyltransferase DNMT3A deposits high levels of non-CG cytosine methylation in neurons. This unique methylation is critical for transcriptional regulation in the mature mammalian brain, and loss of this mark is implicated in DNMT3A-associated neurodevelopmental...

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Detalles Bibliográficos
Autores principales: Hamagami, Nicole, Wu, Dennis Y., Clemens, Adam W., Nettles, Sabin A., Gabel, Harrison W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949142/
https://www.ncbi.nlm.nih.gov/pubmed/36824816
http://dx.doi.org/10.1101/2023.02.17.528965

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