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Association of Polygenic Score and the involvement of Cholinergic and Glutamatergic Pathways with Lithium Treatment Response in Patients with Bipolar Disorder

Lithium is regarded as the first-line treatment for bipolar disorder (BD), a severe and disabling mental disorder that affects about 1% of the population worldwide. Nevertheless, lithium is not consistently effective, with only 30% of patients showing a favorable response to treatment. To provide pe...

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Autores principales: Amare, Azmeraw, Thalamuthu, Anbupalam, Schubert, Klaus Oliver, Fullerton, Janice, Ahmed, Muktar, Hartmann, Simon, Papiol, Sergi, Heilbronner, Urs, Degenhardt, Franziska, Tekola-Ayele, Fasil, Hou, Liping, Hsu, Yi-Hsiang, Shekhtman, Tatyana, Adli, Mazda, Akula, Nirmala, Akiyama, Kazufumi, Ardau, Raffaella, Arias, Bárbara, Aubry, Jean-Michel, Backlund, Lena, Bhattacharjee, Abesh Kumar, Bellivier, Frank, Benabarre, Antoni, Bengesser, Susanne, Biernacka, Joanna, Birner, Armin, Marie-Claire, Cynthia, Cervantes, Pablo, Chen, Hsi-Chung, Chillotti, Caterina, Cichon, Sven, Cruceanu, Cristiana, Czerski, Piotr, Dalkner, Nina, Del Zompo, Maria, DePaulo, J. Raymond, Etain, Bruno, Jamain, Stéphane, Falkai, Peter, Forstner, Andreas J., Frisén, Louise, Frye, Mark, Gard, Sébastien, Garnham, Julie, Goes, Fernando, Grigoroiu-Serbanescu, Maria, Fallgatter, Andreas, Stegmaier, Sophia, Ethofer, Thomas, Biere, Silvia, Petrova, Kristiyana, Schuster, Ceylan, Adorjan, Kristina, Budde, Monika, Heilbronner, Maria, Kalman, Janos, Oraki Kohshour, Mojtaba, Reich-Erkelenz, Daniela, Schaupp, Sabrina, Schulte, Eva, Senner, Fanny, Vogl, Thomas, Anghelescu, Ion-George, Arolt, Volker, Dannlowski, Udo, Dietrich, Detlef E., Figge, Christian, Jäger, Markus, Lang, Fabian, Juckel, Georg, Spitzer, Carsten, Reimer, Jens, Schmauß, Max, Schmitt, Andrea, Konrad, Carsten, von Hagen, Martin, Wiltfang, Jens, Zimmermann, Jörg, Andlauer, Till, Fischer, Andre, Bermpohl, Felix, Kraft, Vivien, Matura, Silke, Gryaznova, Anna, Falkenberg, Irina, Yildiz, Cüneyt, Kircher, Tilo, Schmidt, Julia, Koch, Marius, Gade, Katrin, Trost, Sarah, Haußleiter, Ida, Lambert, Martin, Rohenkohl, Anja C., Grof, Paul, Hashimoto, Ryota, Hauser, Joanna, Herms, Stefan, Hoffmann, Per, Jiménez, Esther, Kahn, Jean-Pierre, Kassem, Layla, kuo, Po-Hsiu, Kato, Tadafumi, Kelsoe, John, Kittel-Schneider, Sarah, Ferensztajn-Rochowiak, Ewa, König, Barbara, Kusumi, Ichiro, Laje, Gonzalo, Landén, Mikael, Lavebratt, Catharina, Leboyer, Marion, Leckband, Susan G., Tortorella, Alfonso, Manchia, Mirko, Martinsson, Lina, McCarthy, Michael, McElroy, Susan L., Colom, Francesc, Mitjans, Marina, Mondimore, Francis, Monteleone, Palmiero, Nievergelt, Caroline, Nöthen, Markus, Novak, Tomas, O’Donovan, Claire, Ozaki, Norio, Pfennig, Andrea, Pisanu, Claudia, Potash, James, Reif, Andreas, Reininghaus, Eva, Rouleau, Guy, Rybakowski, Janusz K., Schalling, Martin, Schofield, Peter, Schweizer, Barbara W., Severino, Giovanni, Shilling, Paul D, Shimoda, Kazutaka, Simhandl, Christian, Slaney, Claire, Squassina, Alessio, Stamm, Thomas, Stopkova, Pavla, Maj, Mario, Turecki, Gustavo, Vieta, Eduard, Veeh, Julia, Witt, Stephanie, Wright, Adam, Zandi, Peter, Mitchell, Philip, Bauer, Michael, Alda, Martin, Rietschel, Marcella, McMahon, Francis, Schulze, Thomas G., Millischer, Vincent, Clark, Scott, Baune, Bernhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949170/
https://www.ncbi.nlm.nih.gov/pubmed/36824922
http://dx.doi.org/10.21203/rs.3.rs-2580252/v1

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