Cargando…
E2F1 Mediates SOX17 Deficiency-Induced Pulmonary Hypertension
RATIONALE: Rare genetic variants and genetic variation at loci in an enhancer in SRY-Box Transcription Factor 17 (SOX17) are identified in patients with idiopathic pulmonary arterial hypertension (PAH) and PAH with congenital heart disease. However, the exact role of genetic variants or mutation in...
Autores principales: | Yi, Dan, Liu, Bin, Ding, Hongxu, Li, Shuai, Li, Rebecca, Pan, Jiakai, Ramirez, Karina, Xia, Xiaomei, Kala, Mrinalini, Singh, Indrapal, Ye, Qinmao, Lee, Won Hee, Frye, Richard E., Wang, Ting, Zhao, Yutong, Knox, Kenneth S., Glembotski, Christopher C., Fallon, Michael B., Dai, Zhiyu |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949178/ https://www.ncbi.nlm.nih.gov/pubmed/36824855 http://dx.doi.org/10.1101/2023.02.15.528740 |
Ejemplares similares
-
SOX17 Deficiency Mediates Pulmonary Hypertension: At the Crossroads of Sex, Metabolism, and Genetics
por: Sangam, Shreya, et al.
Publicado: (2023) -
Suppression of BMP signaling by PHD2 deficiency in Pulmonary Arterial hypertension
por: Liu, Bin, et al.
Publicado: (2022) -
Sox17 Deficiency Promotes Pulmonary Arterial Hypertension via HGF/c-Met Signaling
por: Park, Chan Soon, et al.
Publicado: (2022) -
Sox7, Sox17, and Sox18 Cooperatively Regulate Vascular Development in the Mouse Retina
por: Zhou, Yulian, et al.
Publicado: (2015) -
SOX17 at the Intersection of Sex, Transcription, and Metabolism in Pulmonary Hypertension
por: Lin, Susan M., et al.
Publicado: (2023)