Integrated analyses reveal a hinge glycan regulates coronavirus spike tilting and virus infectivity

Coronavirus spike glycoproteins presented on the virion surface mediate receptor binding, and membrane fusion during virus entry and constitute the primary target for vaccine and drug development. How the structure dynamics of the full-length spikes incorporated in viral lipid envelope correlates wi...

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Detalles Bibliográficos
Autores principales: Chmielewski, David, Wilson, Eric A., Pintilie, Grigore, Zhao, Peng, Chen, Muyuan, Schmid, Michael F., Simmons, Graham, Wells, Lance, Jin, Jing, Singharoy, Abhishek, Chiu, Wah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949256/
https://www.ncbi.nlm.nih.gov/pubmed/36824920
http://dx.doi.org/10.21203/rs.3.rs-2553619/v1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949256/
https://www.ncbi.nlm.nih.gov/pubmed/36824920
http://dx.doi.org/10.21203/rs.3.rs-2553619/v1

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