An Optimized GATK4 Pipeline for Plasmodium falciparum Whole Genome Sequencing Variant Calling and Analysis

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BACKGROUND: Accurate variant calls from whole genome sequencing (WGS) of Plasmodium falciparum infections are crucial in malaria population genomics. Here we optimized a falciparum variant calling pipeline based on GATK version 4 (GATK4) and applied it to 6,626 public Illumina WGS samples. METHODS:...

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Detalles Bibliográficos
Autores principales: Niaré, Karamoko, Greenhouse, Bryan, Bailey, Jeffrey A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Journal Experts 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949269/
https://www.ncbi.nlm.nih.gov/pubmed/36824880
http://dx.doi.org/10.21203/rs.3.rs-2561857/v1

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