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Recent advances in lanthanide-doped up-conversion probes for theranostics

Up-conversion (or anti-Stokes) luminescence refers to the phenomenon whereby materials emit high energy, short-wavelength light upon excitation at longer wavelengths. Lanthanide-doped up-conversion nanoparticles (Ln-UCNPs) are widely used in biomedicine due to their excellent physical and chemical p...

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Autores principales: Xu, Danyang, Li, Chenxu, Li, Wenjing, Lin, Bi, Lv, Ruichan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949555/
https://www.ncbi.nlm.nih.gov/pubmed/36846851
http://dx.doi.org/10.3389/fchem.2023.1036715
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author Xu, Danyang
Li, Chenxu
Li, Wenjing
Lin, Bi
Lv, Ruichan
author_facet Xu, Danyang
Li, Chenxu
Li, Wenjing
Lin, Bi
Lv, Ruichan
author_sort Xu, Danyang
collection PubMed
description Up-conversion (or anti-Stokes) luminescence refers to the phenomenon whereby materials emit high energy, short-wavelength light upon excitation at longer wavelengths. Lanthanide-doped up-conversion nanoparticles (Ln-UCNPs) are widely used in biomedicine due to their excellent physical and chemical properties such as high penetration depth, low damage threshold and light conversion ability. Here, the latest developments in the synthesis and application of Ln-UCNPs are reviewed. First, methods used to synthesize Ln-UCNPs are introduced, and four strategies for enhancing up-conversion luminescence are analyzed, followed by an overview of the applications in phototherapy, bioimaging and biosensing. Finally, the challenges and future prospects of Ln-UCNPs are summarized.
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spelling pubmed-99495552023-02-24 Recent advances in lanthanide-doped up-conversion probes for theranostics Xu, Danyang Li, Chenxu Li, Wenjing Lin, Bi Lv, Ruichan Front Chem Chemistry Up-conversion (or anti-Stokes) luminescence refers to the phenomenon whereby materials emit high energy, short-wavelength light upon excitation at longer wavelengths. Lanthanide-doped up-conversion nanoparticles (Ln-UCNPs) are widely used in biomedicine due to their excellent physical and chemical properties such as high penetration depth, low damage threshold and light conversion ability. Here, the latest developments in the synthesis and application of Ln-UCNPs are reviewed. First, methods used to synthesize Ln-UCNPs are introduced, and four strategies for enhancing up-conversion luminescence are analyzed, followed by an overview of the applications in phototherapy, bioimaging and biosensing. Finally, the challenges and future prospects of Ln-UCNPs are summarized. Frontiers Media S.A. 2023-02-09 /pmc/articles/PMC9949555/ /pubmed/36846851 http://dx.doi.org/10.3389/fchem.2023.1036715 Text en Copyright © 2023 Xu, Li, Li, Lin and Lv. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Chemistry
Xu, Danyang
Li, Chenxu
Li, Wenjing
Lin, Bi
Lv, Ruichan
Recent advances in lanthanide-doped up-conversion probes for theranostics
title Recent advances in lanthanide-doped up-conversion probes for theranostics
title_full Recent advances in lanthanide-doped up-conversion probes for theranostics
title_fullStr Recent advances in lanthanide-doped up-conversion probes for theranostics
title_full_unstemmed Recent advances in lanthanide-doped up-conversion probes for theranostics
title_short Recent advances in lanthanide-doped up-conversion probes for theranostics
title_sort recent advances in lanthanide-doped up-conversion probes for theranostics
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949555/
https://www.ncbi.nlm.nih.gov/pubmed/36846851
http://dx.doi.org/10.3389/fchem.2023.1036715
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