Innate sensing pathways: Defining new innate immune and inflammatory cell death pathways has shaped translational applications

The past 20 years of research has elucidated new innate immune sensing and cell death pathways with disease relevance. Future molecular characterization of these pathways and their crosstalk and functional redundancies will aid in development of therapeutic strategies.

Detalles Bibliográficos
Autores principales: Tweedell, Rebecca E., Kumar, Sivakumar Prasanth, Kanneganti, Thirumala-Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949619/
https://www.ncbi.nlm.nih.gov/pubmed/36763683
http://dx.doi.org/10.1371/journal.pbio.3002022
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author Tweedell, Rebecca E.
Kumar, Sivakumar Prasanth
Kanneganti, Thirumala-Devi
author_facet Tweedell, Rebecca E.
Kumar, Sivakumar Prasanth
Kanneganti, Thirumala-Devi
author_sort Tweedell, Rebecca E.
collection PubMed
description The past 20 years of research has elucidated new innate immune sensing and cell death pathways with disease relevance. Future molecular characterization of these pathways and their crosstalk and functional redundancies will aid in development of therapeutic strategies.
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spelling pubmed-99496192023-02-24 Innate sensing pathways: Defining new innate immune and inflammatory cell death pathways has shaped translational applications Tweedell, Rebecca E. Kumar, Sivakumar Prasanth Kanneganti, Thirumala-Devi PLoS Biol Perspective The past 20 years of research has elucidated new innate immune sensing and cell death pathways with disease relevance. Future molecular characterization of these pathways and their crosstalk and functional redundancies will aid in development of therapeutic strategies. Public Library of Science 2023-02-10 /pmc/articles/PMC9949619/ /pubmed/36763683 http://dx.doi.org/10.1371/journal.pbio.3002022 Text en © 2023 Tweedell et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Perspective
Tweedell, Rebecca E.
Kumar, Sivakumar Prasanth
Kanneganti, Thirumala-Devi
Innate sensing pathways: Defining new innate immune and inflammatory cell death pathways has shaped translational applications
title Innate sensing pathways: Defining new innate immune and inflammatory cell death pathways has shaped translational applications
title_full Innate sensing pathways: Defining new innate immune and inflammatory cell death pathways has shaped translational applications
title_fullStr Innate sensing pathways: Defining new innate immune and inflammatory cell death pathways has shaped translational applications
title_full_unstemmed Innate sensing pathways: Defining new innate immune and inflammatory cell death pathways has shaped translational applications
title_short Innate sensing pathways: Defining new innate immune and inflammatory cell death pathways has shaped translational applications
title_sort innate sensing pathways: defining new innate immune and inflammatory cell death pathways has shaped translational applications
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949619/
https://www.ncbi.nlm.nih.gov/pubmed/36763683
http://dx.doi.org/10.1371/journal.pbio.3002022
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