Cargando…

Infrastructure for bioinformatics applications in Tanzania: Lessons from the Sickle Cell Programme

Sickle cell disease (SCD) is a common genetic disorder in Africa. Some ongoing work in SCD research includes the analysis and comparisons of variation in phenotypic presentations and disease outcomes with the genotypic signatures. This has contributed to the observed growth of molecular and genetic...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mwita, Liberata A., Mawalla, William F., Mtiiye, Frank R., Kandonga, Daniel, Kent, Jill, Makani, Julie, Sangeda, Raphael Z.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2023
Materias:	Perspective
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949651/ https://www.ncbi.nlm.nih.gov/pubmed/36821534 http://dx.doi.org/10.1371/journal.pcbi.1010848

Ejemplares similares

Patterns and patient factors associated with loss to follow-up in the Muhimbili sickle cell cohort, Tanzania
por: Masamu, Upendo, et al.
Publicado: (2020)

Identifying genetic variants and pathways associated with extreme levels of fetal hemoglobin in sickle cell disease in Tanzania
por: Nkya, Siana, et al.
Publicado: (2020)

A common molecular signature of patients with sickle cell disease revealed by microarray meta-analysis and a genome-wide association study
por: Ben Hamda, Cherif, et al.
Publicado: (2018)

Possible Risk Factors for Severe Anemia in Hospitalized Sickle Cell Patients at Muhimbili National Hospital, Tanzania: Protocol for a Cross-Sectional Study
por: Tluway, Furahini, et al.
Publicado: (2018)

Nasopharyngeal Carriage and Antibiogram of Pneumococcal and Other Bacterial Pathogens from Children with Sickle Cell Disease in Tanzania
por: Mutagonda, Ritah F, et al.
Publicado: (2022)

A ten year review of the sickle cell program in Muhimbili National Hospital, Tanzania
por: Makani, Julie, et al.
Publicado: (2018)

Building research capacity for sickle cell disease in Africa: Lessons and challenges from establishing a birth cohort in Tanzania
por: Nkya, Siana, et al.
Publicado: (2022)

Utilization patterns of malaria chemoprophylaxis among Tanzanian children attending sickle cell clinic in Dar es Salaam tertiary hospitals
por: Ndegeulaya, Esther J., et al.
Publicado: (2019)

Relationships between sickle cell trait, malaria, and educational outcomes in Tanzania
por: Croke, Kevin, et al.
Publicado: (2017)

Perspectives on Building Sustainable Newborn Screening Programs for Sickle Cell Disease: Experience from Tanzania
por: Bukini, Daima, et al.
Publicado: (2021)

Prevalence and Factors Associated with Human Parvovirus B19 Infection in Sickle Cell Patients Hospitalized in Tanzania
por: Urio, Florence, et al.
Publicado: (2019)

Genetic variants at HbF‐modifier loci moderate anemia and leukocytosis in sickle cell disease in Tanzania
por: Mtatiro, Siana Nkya, et al.
Publicado: (2014)

Resilient Clinical Trial Infrastructure in Response to the COVID-19 Pandemic: Lessons Learned from the TOGETHER Randomized Platform Clinical Trial
por: Forrest, Jamie I., et al.
Publicado: (2022)

Microbiological Quality of Selected Local and Imported Non-Sterile Pharmaceutical Products in Dar es Salaam, Tanzania
por: Myemba, David T, et al.
Publicado: (2022)

Fetal Hemoglobin is Associated with Peripheral Oxygen Saturation in Sickle Cell Disease in Tanzania
por: Nkya, Siana, et al.
Publicado: (2017)

Healthcare Workers’ Knowledge and Resource Availability for Care of Sickle Cell Disease in Dar es Salaam, Tanzania
por: Jonathan, Agnes, et al.
Publicado: (2022)

Using DNA testing for the precise, definite, and low-cost diagnosis of sickle cell disease and other Haemoglobinopathies: findings from Tanzania
por: Christopher, Heavenlight, et al.
Publicado: (2021)

Establishing a Multi-Country Sickle Cell Disease Registry in Africa: Ethical Considerations
por: Munung, Nchangwi Syntia, et al.
Publicado: (2019)

Genome Wide Association Study of Fetal Hemoglobin in Sickle Cell Anemia in Tanzania
por: Mtatiro, Siana Nkya, et al.
Publicado: (2014)

Health policy for sickle cell disease in Africa: experience from Tanzania on interventions to reduce under-five mortality
por: Makani, Julie, et al.
Publicado: (2014)

Decreased Hepcidin Levels Are Associated with Low Steady-state Hemoglobin in Children With Sickle Cell Disease in Tanzania
por: Lee, Nathaniel, et al.
Publicado: (2018)

Mortality in Sickle Cell Anemia in Africa: A Prospective Cohort Study in Tanzania
por: Makani, Julie, et al.
Publicado: (2011)

Pharmacists’ Knowledge, Attitude and Practice Regarding the Dispensing of Antibiotics without Prescription in Tanzania: An Explorative Cross-Sectional Study
por: Poyongo, Baraka P., et al.
Publicado: (2020)

Making hydroxyurea affordable for sickle cell disease in Tanzania is essential (HASTE): How to meet major health needs at a reasonable cost
por: Costa, Enrico, et al.
Publicado: (2020)

The clinical presentation, utilization, and outcome of individuals with sickle cell anaemia presenting to urban emergency department of a tertiary hospital in Tanzania
por: Sawe, Hendry R., et al.
Publicado: (2018)

Sickle cell disease in Africa: an urgent need for longitudinal cohort studies
por: Wonkam, Ambroise, et al.
Publicado: (2019)

The Roots of Bioinformatics
por: Searls, David B.
Publicado: (2010)

On Bioinformatic Resources
por: Chen, Runsheng
Publicado: (2015)

Is “bioinformatics” dead?
por: Bourne, Philip E.
Publicado: (2021)

Converging Currents in Climate-Relevant Conservation: Water, Infrastructure, and Institutions
por: Matthews, John H., et al.
Publicado: (2011)

Fostering incidental experiences of nature through green infrastructure planning
por: Beery, Thomas H., et al.
Publicado: (2017)

Beyond advertising: New infrastructures for publishing integrated research objects
por: DuPre, Elizabeth, et al.
Publicado: (2022)

Skills Capacity Building For Health Care Services and Research Through the Sickle Pan African Research Consortium
por: Nnodu, Obiageli Eunice, et al.
Publicado: (2022)

Sickle Cell Anaemia in a Changing World
por: Fottrell, Edward, et al.
Publicado: (2013)

Sickle cell disease in India: A perspective
por: Serjeant, Graham R., et al.
Publicado: (2016)

The Effects of Sickle Cell Disease on the Quality of Life: A Focus on the Untold Experiences of Parents in Tanzania
por: Kilonzi, Manase, et al.
Publicado: (2022)

Isolation Frequency of Fluconazole-Resistant Candida Species From Cockroaches: A Cross-Sectional Study From a National Hospital in Dar es Salaam, Tanzania
por: Mloka, Doreen, et al.
Publicado: (2022)

An Online Bioinformatics Curriculum
por: Searls, David B.
Publicado: (2012)

Limited Exchange Transfusion Can Be Very Beneficial in Sickle Cell Anemia with Acute Chest Syndrome: A Case Report from Tanzania
por: Chamba, Clara, et al.
Publicado: (2018)

Prevalence of urinary tract infection and antimicrobial resistance patterns of uropathogens with biofilm forming capacity among outpatients in morogoro, Tanzania: a cross-sectional study
por: Mlugu, Eulambius M., et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_nikst0matph425i7oihp0lafvn