Salivary gland LAMP3 mRNA expression is a possible predictive marker in the response to hydroxychloroquine in Sjögren’s disease

Hydroxychloroquine (HCQ) is a lysosomotropic agent that is commonly used for treating Sjögren’s disease (SjD). However, its efficacy is controversial because of the divergent response to the drug among patients. In a subgroup of SjD patients, lysosome-associated membrane protein 3 (LAMP3) is elevate...

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Detalles Bibliográficos
Autores principales: Nakamura, Hiroyuki, Tanaka, Tsutomu, Ji, Youngmi, Zheng, Changyu, Afione, Sandra A., Warner, Blake M., Oliveira, Fabiola Reis, Motta, Ana Carolina F., Rocha, Eduardo M., Noguchi, Masayuki, Atsumi, Tatsuya, Chiorini, John A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949663/
https://www.ncbi.nlm.nih.gov/pubmed/36821638
http://dx.doi.org/10.1371/journal.pone.0282227

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