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Effects of metformin and statins on outcomes in men with castration-resistant metastatic prostate cancer: Secondary analysis of COU-AA-301 and COU-AA-302

BACKGROUND: The associations of metformin and statins with overall survival (OS) and prostate specific antigen response rate (PSA-RR) in trials in metastatic castration-resistant prostate cancer remain unclear. OBJECTIVE: To determine whether metformin or statins ± abiraterone acetate plus prednison...

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Detalles Bibliográficos
Autores principales: Wilson, Brooke E., Armstrong, Andrew J., de Bono, Johann, Sternberg, Cora N., Ryan, Charles J., Scher, Howard I., Smith, Matthew R., Rathkopf, Dana, Logothetis, Christopher J., Chi, Kim N., Jones, Robert J., Saad, Fred, De Porre, Peter, Tran, NamPhuong, Hu, Peter, Gillessen, Silke, Carles, Joan, Fizazi, Karim, Joshua, Anthony M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949683/
https://www.ncbi.nlm.nih.gov/pubmed/35568679
http://dx.doi.org/10.1016/j.ejca.2022.03.042