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AI-enhanced protein design makes proteins that have never existed
Protein engineers are drawing on rapidly evolving machine learning tools, deep reservoirs of data, and the structure-predicting firepower of AlphaFold2 to pursue more sophisticated de novo protein designs.
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group US
2023
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949690/ https://www.ncbi.nlm.nih.gov/pubmed/36823357 http://dx.doi.org/10.1038/s41587-023-01705-y |
| _version_ | 1784893000583741440 |
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| author | Eisenstein, Michael |
| author_facet | Eisenstein, Michael |
| author_sort | Eisenstein, Michael |
| collection | PubMed |
| description | Protein engineers are drawing on rapidly evolving machine learning tools, deep reservoirs of data, and the structure-predicting firepower of AlphaFold2 to pursue more sophisticated de novo protein designs. |
| format | Online Article Text |
| id | pubmed-9949690 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2023 |
| publisher | Nature Publishing Group US |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-99496902023-02-24 AI-enhanced protein design makes proteins that have never existed Eisenstein, Michael Nat Biotechnol News Protein engineers are drawing on rapidly evolving machine learning tools, deep reservoirs of data, and the structure-predicting firepower of AlphaFold2 to pursue more sophisticated de novo protein designs. Nature Publishing Group US 2023-02-23 2023 /pmc/articles/PMC9949690/ /pubmed/36823357 http://dx.doi.org/10.1038/s41587-023-01705-y Text en © The Author(s), under exclusive licence to Springer Nature America, Inc. 2023 This article is made available via the PMC Open Access Subset for unrestricted research re-use and secondary analysis in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the World Health Organization (WHO) declaration of COVID-19 as a global pandemic. |
| spellingShingle | News Eisenstein, Michael AI-enhanced protein design makes proteins that have never existed |
| title | AI-enhanced protein design makes proteins that have never existed |
| title_full | AI-enhanced protein design makes proteins that have never existed |
| title_fullStr | AI-enhanced protein design makes proteins that have never existed |
| title_full_unstemmed | AI-enhanced protein design makes proteins that have never existed |
| title_short | AI-enhanced protein design makes proteins that have never existed |
| title_sort | ai-enhanced protein design makes proteins that have never existed |
| topic | News |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949690/ https://www.ncbi.nlm.nih.gov/pubmed/36823357 http://dx.doi.org/10.1038/s41587-023-01705-y |
| work_keys_str_mv | AT eisensteinmichael aienhancedproteindesignmakesproteinsthathaveneverexisted |