The landscape of antibody binding affinity in SARS-CoV-2 Omicron BA.1 evolution

The Omicron BA.1 variant of SARS-CoV-2 escapes convalescent sera and monoclonal antibodies that are effective against earlier strains of the virus. This immune evasion is largely a consequence of mutations in the BA.1 receptor binding domain (RBD), the major antigenic target of SARS-CoV-2. Previous...

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Detalles Bibliográficos
Autores principales: Moulana, Alief, Dupic, Thomas, Phillips, Angela M, Chang, Jeffrey, Roffler, Anne A, Greaney, Allison J, Starr, Tyler N, Bloom, Jesse D, Desai, Michael M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2023
Materias:
Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949795/
https://www.ncbi.nlm.nih.gov/pubmed/36803543
http://dx.doi.org/10.7554/eLife.83442

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949795/
https://www.ncbi.nlm.nih.gov/pubmed/36803543
http://dx.doi.org/10.7554/eLife.83442

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