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Culture and sensitivity pattern of aerobic bacterial isolates in diabetic foot infections during 2018–2022 in Asian countries: a literature review study

The most prevalent consequence of diabetes mellitus is diabetic foot infections (DFIs). Prior to the final treatment established by the culture findings, the early identification of infections may be used as a prescription for an empirical therapy. This study examines the microbiological profile and...

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Autores principales: Huwae, Thomas E.C.J., Ratridewi, Irene, Lena, Yulanda M., Retnoningsih, Dewi, Sananta, Panji, Asmiragani, Syaifullah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949823/
https://www.ncbi.nlm.nih.gov/pubmed/36845791
http://dx.doi.org/10.1097/MS9.0000000000000223
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author Huwae, Thomas E.C.J.
Ratridewi, Irene
Lena, Yulanda M.
Retnoningsih, Dewi
Sananta, Panji
Asmiragani, Syaifullah
author_facet Huwae, Thomas E.C.J.
Ratridewi, Irene
Lena, Yulanda M.
Retnoningsih, Dewi
Sananta, Panji
Asmiragani, Syaifullah
author_sort Huwae, Thomas E.C.J.
collection PubMed
description The most prevalent consequence of diabetes mellitus is diabetic foot infections (DFIs). Prior to the final treatment established by the culture findings, the early identification of infections may be used as a prescription for an empirical therapy. This study examines the microbiological profile and antimicrobial susceptibility profile of the bacteria that cause DFI. METHODS: This research aims to determine the culture and sensitivity trend of aerobic bacterial isolates of DFI in Asian nations over a 5-year period. The article was searched using PubMed and Google Scholar with the keywords ‘Diabetic Foot Infections’, ‘Antibiotic’, ‘Microbiological Profile’, and their combinations. The author uses publications from 2018 to 2022 in Indonesian and English to select the appropriate journal. RESULTS: The author identified 11 relevant articles with microbiological profiles and sensitivity patterns in DFI. A total of 3097 isolates were found in 2498 patients with DFI. Gram-negative bacteria were the leading source of infection (n=1737; 56%). Totally, 1148 (or 37%) of all isolates were aerobic Gram-positive cocci. Staphylococcus aureus was the most commonly isolated aerobe (n=608, 20%), followed by Pseudomonas aeruginosa (n=451, 15%). Gram-positive bacteria showed good susceptibility to trimethoprim-sulfamethoxazole, chloramphenicol, doxycycline, vancomycin, and linezolid. Gram-negative bacteria displayed excellent susceptibility to aminoglycosides, piperacillin-tazobactam, and carbapenems. CONCLUSIONS: Gram-negative microorganisms were the most prevalent cause of DFI. This study’s findings will facilitate the development of future empirical therapeutic guidelines for the treatment of DFI.
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spelling pubmed-99498232023-02-24 Culture and sensitivity pattern of aerobic bacterial isolates in diabetic foot infections during 2018–2022 in Asian countries: a literature review study Huwae, Thomas E.C.J. Ratridewi, Irene Lena, Yulanda M. Retnoningsih, Dewi Sananta, Panji Asmiragani, Syaifullah Ann Med Surg (Lond) Original Research The most prevalent consequence of diabetes mellitus is diabetic foot infections (DFIs). Prior to the final treatment established by the culture findings, the early identification of infections may be used as a prescription for an empirical therapy. This study examines the microbiological profile and antimicrobial susceptibility profile of the bacteria that cause DFI. METHODS: This research aims to determine the culture and sensitivity trend of aerobic bacterial isolates of DFI in Asian nations over a 5-year period. The article was searched using PubMed and Google Scholar with the keywords ‘Diabetic Foot Infections’, ‘Antibiotic’, ‘Microbiological Profile’, and their combinations. The author uses publications from 2018 to 2022 in Indonesian and English to select the appropriate journal. RESULTS: The author identified 11 relevant articles with microbiological profiles and sensitivity patterns in DFI. A total of 3097 isolates were found in 2498 patients with DFI. Gram-negative bacteria were the leading source of infection (n=1737; 56%). Totally, 1148 (or 37%) of all isolates were aerobic Gram-positive cocci. Staphylococcus aureus was the most commonly isolated aerobe (n=608, 20%), followed by Pseudomonas aeruginosa (n=451, 15%). Gram-positive bacteria showed good susceptibility to trimethoprim-sulfamethoxazole, chloramphenicol, doxycycline, vancomycin, and linezolid. Gram-negative bacteria displayed excellent susceptibility to aminoglycosides, piperacillin-tazobactam, and carbapenems. CONCLUSIONS: Gram-negative microorganisms were the most prevalent cause of DFI. This study’s findings will facilitate the development of future empirical therapeutic guidelines for the treatment of DFI. Lippincott Williams & Wilkins 2023-02-17 /pmc/articles/PMC9949823/ /pubmed/36845791 http://dx.doi.org/10.1097/MS9.0000000000000223 Text en © 2023 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (https://creativecommons.org/licenses/by-nc-nd/4.0/) (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal. http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/)
spellingShingle Original Research
Huwae, Thomas E.C.J.
Ratridewi, Irene
Lena, Yulanda M.
Retnoningsih, Dewi
Sananta, Panji
Asmiragani, Syaifullah
Culture and sensitivity pattern of aerobic bacterial isolates in diabetic foot infections during 2018–2022 in Asian countries: a literature review study
title Culture and sensitivity pattern of aerobic bacterial isolates in diabetic foot infections during 2018–2022 in Asian countries: a literature review study
title_full Culture and sensitivity pattern of aerobic bacterial isolates in diabetic foot infections during 2018–2022 in Asian countries: a literature review study
title_fullStr Culture and sensitivity pattern of aerobic bacterial isolates in diabetic foot infections during 2018–2022 in Asian countries: a literature review study
title_full_unstemmed Culture and sensitivity pattern of aerobic bacterial isolates in diabetic foot infections during 2018–2022 in Asian countries: a literature review study
title_short Culture and sensitivity pattern of aerobic bacterial isolates in diabetic foot infections during 2018–2022 in Asian countries: a literature review study
title_sort culture and sensitivity pattern of aerobic bacterial isolates in diabetic foot infections during 2018–2022 in asian countries: a literature review study
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949823/
https://www.ncbi.nlm.nih.gov/pubmed/36845791
http://dx.doi.org/10.1097/MS9.0000000000000223
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