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Onset of Mucormycosis in Patients with COVID-19: A Systematic Review on Patients' Characteristics

Mucormycosis has a significant impact on patients' standard of living and, therefore, a high clinical suspicion, prediagnosis, and rapid treatment are critical in easing patients' suffering and fast recovery. Our focus is to conduct an organized review based on various variables on the pat...

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Autores principales: Ghasemi, Shohreh, Dashti, Mahmood, Fahimipour, Amir, Daryakenari, Ghazaleh, Mirzaei, Fatemeh, Akbari, Fatemeh, Khurshid, Zohaib
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949939/
https://www.ncbi.nlm.nih.gov/pubmed/36049777
http://dx.doi.org/10.1055/s-0042-1751003
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author Ghasemi, Shohreh
Dashti, Mahmood
Fahimipour, Amir
Daryakenari, Ghazaleh
Mirzaei, Fatemeh
Akbari, Fatemeh
Khurshid, Zohaib
author_facet Ghasemi, Shohreh
Dashti, Mahmood
Fahimipour, Amir
Daryakenari, Ghazaleh
Mirzaei, Fatemeh
Akbari, Fatemeh
Khurshid, Zohaib
author_sort Ghasemi, Shohreh
collection PubMed
description Mucormycosis has a significant impact on patients' standard of living and, therefore, a high clinical suspicion, prediagnosis, and rapid treatment are critical in easing patients' suffering and fast recovery. Our focus is to conduct an organized review based on various variables on the patients' characteristics having mucormycosis in severe novel coronavirus disease 2019 (COVID-19). We examined Embase, PubMed-Medline, LitCovid, Web of Science, Scopus, and the reference lists of included case reports up to September 20, 2021, using the Medical Subject Heading (MeSH) phrases and other keywords related to this topic. Subsequently, we investigated associated comorbidities, patient characteristics, position of mucormycosis, steroids use, body involvements, and outcomes. Overall, 77 studies were conducted and among these, 72 studies mentioned that the patients' age to be 48.13±14.33 (mean±standard deviation [SD]) years. Diabetes mellitus (DM) was reported in 77.9% ( n =60) of cases. Studies showed that central nervous system (CNS) and bone involvement were reported in 62.3 ( n =48) and 53.2% ( n =41), respectively. More fatalities were observed in patients with mucormycosis with the active form of COVID-19. Also, men infected with mucormycosis significantly affected by COVID-19. In the end, mortality was higher in males with mucormycosis. As a result, a solid investigation into the root cause of mucormycosis, especially in COVID-19, should be included in the study plan. If the patient is COVID-19-positive and immunosuppressed, this opportunistic pathogen diagnostic test should not be overlooked.
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spelling pubmed-99499392023-02-24 Onset of Mucormycosis in Patients with COVID-19: A Systematic Review on Patients' Characteristics Ghasemi, Shohreh Dashti, Mahmood Fahimipour, Amir Daryakenari, Ghazaleh Mirzaei, Fatemeh Akbari, Fatemeh Khurshid, Zohaib Eur J Dent Mucormycosis has a significant impact on patients' standard of living and, therefore, a high clinical suspicion, prediagnosis, and rapid treatment are critical in easing patients' suffering and fast recovery. Our focus is to conduct an organized review based on various variables on the patients' characteristics having mucormycosis in severe novel coronavirus disease 2019 (COVID-19). We examined Embase, PubMed-Medline, LitCovid, Web of Science, Scopus, and the reference lists of included case reports up to September 20, 2021, using the Medical Subject Heading (MeSH) phrases and other keywords related to this topic. Subsequently, we investigated associated comorbidities, patient characteristics, position of mucormycosis, steroids use, body involvements, and outcomes. Overall, 77 studies were conducted and among these, 72 studies mentioned that the patients' age to be 48.13±14.33 (mean±standard deviation [SD]) years. Diabetes mellitus (DM) was reported in 77.9% ( n =60) of cases. Studies showed that central nervous system (CNS) and bone involvement were reported in 62.3 ( n =48) and 53.2% ( n =41), respectively. More fatalities were observed in patients with mucormycosis with the active form of COVID-19. Also, men infected with mucormycosis significantly affected by COVID-19. In the end, mortality was higher in males with mucormycosis. As a result, a solid investigation into the root cause of mucormycosis, especially in COVID-19, should be included in the study plan. If the patient is COVID-19-positive and immunosuppressed, this opportunistic pathogen diagnostic test should not be overlooked. Thieme Medical and Scientific Publishers Pvt. Ltd. 2022-09-01 /pmc/articles/PMC9949939/ /pubmed/36049777 http://dx.doi.org/10.1055/s-0042-1751003 Text en The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ) https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Ghasemi, Shohreh
Dashti, Mahmood
Fahimipour, Amir
Daryakenari, Ghazaleh
Mirzaei, Fatemeh
Akbari, Fatemeh
Khurshid, Zohaib
Onset of Mucormycosis in Patients with COVID-19: A Systematic Review on Patients' Characteristics
title Onset of Mucormycosis in Patients with COVID-19: A Systematic Review on Patients' Characteristics
title_full Onset of Mucormycosis in Patients with COVID-19: A Systematic Review on Patients' Characteristics
title_fullStr Onset of Mucormycosis in Patients with COVID-19: A Systematic Review on Patients' Characteristics
title_full_unstemmed Onset of Mucormycosis in Patients with COVID-19: A Systematic Review on Patients' Characteristics
title_short Onset of Mucormycosis in Patients with COVID-19: A Systematic Review on Patients' Characteristics
title_sort onset of mucormycosis in patients with covid-19: a systematic review on patients' characteristics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949939/
https://www.ncbi.nlm.nih.gov/pubmed/36049777
http://dx.doi.org/10.1055/s-0042-1751003
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