Cargando…

Mechanisms of Peripheral and Central Sensitization in Osteoarthritis Pain

Pain, the primary symptom of osteoarthritis (OA), reduces both the quality and quantity of life for patients. The pathophysiology of OA pain is complex and often difficult to explain solely by radiological structural changes. One reason for this discrepancy is pain sensitization (peripheral sensitiz...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ohashi, Yoshihisa, Uchida, Kentaro, Fukushima, Kensuke, Inoue, Gen, Takaso, Masashi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cureus 2023
Materias:	Orthopedics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9949992/ https://www.ncbi.nlm.nih.gov/pubmed/36846635 http://dx.doi.org/10.7759/cureus.35331

Ejemplares similares

NGF Expression and Elevation in Hip Osteoarthritis Patients with Pain and Central Sensitization
por: Ohashi, Yoshihisa, et al.
Publicado: (2021)

Differential Synovial CGRP/RAMP1 Expression in Men and Women With Knee Osteoarthritis
por: Uchida, Kentaro, et al.
Publicado: (2021)

Central sensitization inventory scores correlate with pain at rest in patients with hip osteoarthritis: a retrospective study
por: Ohashi, Yoshihisa, et al.
Publicado: (2020)

Adverse Effects of Higher Preoperative Pain at Rest, a Central Sensitization-Related Symptom, on Outcomes After Total Hip Arthroplasty in Patients with Osteoarthritis
por: Ohashi, Yoshihisa, et al.
Publicado: (2021)

Differences in outcomes after total hip arthroplasty for osteoarthritis between patients with and without central sensitivity syndromes other than fibromyalgia
por: Ohashi, Yoshihisa, et al.
Publicado: (2022)

Assessment of the duration and effectiveness of intra-articular lidocaine injections for groin pain in patients with labral tears involving early osteoarthritis
por: Fukushima, Kensuke, et al.
Publicado: (2021)

β2-Microglobulin Elevates COL5A1 mRNA in the Subsynovial Connective Tissue of Patients Receiving Hemodialysis With Carpal Tunnel Syndrome
por: Muneshige, Kyoko, et al.
Publicado: (2022)

Acceleration of Bone Healing by In Situ-Forming Dextran-Tyramine Conjugates Containing Basic Fibroblast Growth Factor in Mice
por: Shoji, Shintaro, et al.
Publicado: (2020)

Effect of Bone Morphogenetic Protein-2 (BMP-2)/Hydroxyapatite/In Situ-Formed Hyaluronan Hydrogel Composites on Bone Formation in a Murine Model of Posterolateral Lumbar Fusion
por: Kuroda, Akiyoshi, et al.
Publicado: (2022)

Elevated levels of TNF-α, IL-1β and IL-6 in the synovial tissue of patients with labral tear: a comparative study with hip osteoarthritis
por: Koyama, Tomohisa, et al.
Publicado: (2021)

CD39+CD55− Fb Subset Exhibits Myofibroblast-Like Phenotype and Is Associated with Pain in Osteoarthritis of the Knee
por: Tsuchiya, Maho, et al.
Publicado: (2023)

Expression of Apelin in Rotator Cuff Tears and Examination of Its Regulatory Mechanism: A Translational Study
por: Nakawaki, Mitsufumi, et al.
Publicado: (2023)

Loop-Mediated Isothermal Amplification Screening for COVID-19 in Asymptomatic Preoperative Orthopedic Patients in a General Hospital in Kanagawa, Japan
por: Uchida, Kentaro, et al.
Publicado: (2020)

Short-Term Impact of Staying Home on Bone Health in Patients With Osteoporosis During a State of Emergency Declaration Due to COVID-19 in Kanagawa, Japan
por: Yokozeki, Yuji, et al.
Publicado: (2020)

Relationships Between Spinal Alignment and Muscle Mass in Osteoporosis Patients Over 75 Years of Age Who Were Independent and Maintained Their Activities of Daily Living
por: Kawakubo, Ayumu, et al.
Publicado: (2021)

In Vivo Evaluation of the Mechanical Strength of a Slide Lengthening Technique With a Locking Mechanism Using a Rabbit Model
por: Iwase, Dai, et al.
Publicado: (2020)

Increase in TPSB2 and TPSD1 Expression in Synovium of Hip Osteoarthritis Patients Who Are Overweight
por: Tsuchiya, Maho, et al.
Publicado: (2023)

Increased Synovial CD14 mRNA Expression and Proportion of CD14(high) Subsets in Early-Stage Hip Osteoarthritis: Propensity Matched Score Analysis
por: Ohashi, Yoshihisa, et al.
Publicado: (2022)

Is bone marrow oedema in patients with labral tear an indicator of hip pain?
por: Koyama, Tomohisa, et al.
Publicado: (2022)

The Relationship Between Falling Distance and Trauma Severity Among Fall Injury Survivors Who Were Transported to a Trauma Center
por: Muneshige, Kyoko, et al.
Publicado: (2022)

TNF-α Suppresses Apelin Receptor Expression in Mouse Quadriceps Femoris-Derived Cells
por: Koyama, Tomohisa, et al.
Publicado: (2022)

Increased NMUR1 Expression in Mast Cells in the Synovial Membrane of Obese Osteoarthritis Patients
por: Tsukada, Ayumi, et al.
Publicado: (2022)

Impact of Jiggling Exercise as Conservative Treatment for Hip Osteoarthritis: A Report of Two Cases
por: Teramoto, Yohei, et al.
Publicado: (2020)

Osteoarthritis of the Manubriosternal Joint: An Uncommon Cause of Chest Pain
por: Vaishya, Raju, et al.
Publicado: (2015)

The cytokine expression in synovial membrane and the relationship with pain and pathological findings at hip arthroscopy
por: Fukushima, Kensuke, et al.
Publicado: (2017)

A Modified Sliding-Lengthening Approach to Tendon Lengthening with a Locking Mechanism Suture: A Technical Note
por: Iwase, Dai, et al.
Publicado: (2023)

Assessing the Awareness Regarding Osteoarthritis and Its Related Risk Factors Among Women in Aseer Central Hospital
por: Almoftery, Ibrahim M, et al.
Publicado: (2023)

Vascular endothelial growth factor expression and their action in the synovial membranes of patients with painful knee osteoarthritis
por: Takano, Shotaro, et al.
Publicado: (2018)

In Vivo Kinematic Analysis of the Axial Shoulder Rotation in the Standing and Supine Positions Using 3D/2D Registration and Electromyography
por: Kenmoku, Tomonori, et al.
Publicado: (2023)

Use of the painDETECT questionnaire to differentiate the nature of hip pain associated with a labrum tear
por: Nakawaki, Mitsufumi, et al.
Publicado: (2017)

Efficacy and Safety of Beta-Tricalcium Phosphate/Polylactic-Co-Glycolic Acid for Implantation of Bone Defects
por: Tokeshi, Soichiro, et al.
Publicado: (2023)

Increase and regulation of synovial calcitonin gene-related peptide expression in patients with painful knee osteoarthritis
por: Takano, Shotaro, et al.
Publicado: (2017)

Mechanical Alignment in Total Knee Arthroplasty for Varus Knee Osteoarthritis Leads to Significant Tibial Bone Loss
por: Mannan, Ashim, et al.
Publicado: (2022)

Bilateral Knee Osteoarthritis Treated With Medial Open-Wedge High Tibial Osteotomy Using Two Types of β-Tricalcium Phosphate With Differing Placements in Each Knee: A Report of Two Cases
por: Mochizuki, Hiromi, et al.
Publicado: (2023)

Efficacy of nerve growth factor antibody in a knee osteoarthritis pain model in mice
por: Miyagi, Masayuki, et al.
Publicado: (2017)

Intra-Articular Leukocyte-Poor Platelet-Rich Plasma Injections for Japanese Patients With Osteoarthritis of the Knee: A Three-Year Observational Retrospective Study After Phase 1 and Phase 2a Trials
por: Taniguchi, Yu, et al.
Publicado: (2022)

Standardized Platelet Rich Plasma Injections for Osteoarthritis of the Knee
por: Ehlers, Cooper B, et al.
Publicado: (2020)

End-Stage Tibiotalar Osteoarthritis and Chronic Strontium Toxicity
por: Ricci, Gianni, et al.
Publicado: (2021)

Elevated macrophage-inducible C-type lectin expression in the synovial tissue of patients with rheumatoid arthritis
por: Takata, Ken, et al.
Publicado: (2021)

Down-regulation of microsomal prostaglandin E2 synthase-1 in the infrapatellar fat pad of osteoarthritis patients with hypercholesterolemia
por: Mukai, Manabu, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_lumj5377cm5j9uep5j6iboeghv