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A CRISPR-Cas9-mediated F0 screen to identify pro-regenerative genes in the zebrafish retinal pigment epithelium

Ocular diseases resulting in death of the retinal pigment epithelium (RPE) lead to vision loss and blindness. There are currently no FDA-approved strategies to restore damaged RPE cells. Stimulating intrinsic regenerative responses within damaged tissues has gained traction as a possible mechanism f...

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Detalles Bibliográficos
Autores principales: Lu, Fangfang, Leach, Lyndsay L., Gross, Jeffrey M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950062/
https://www.ncbi.nlm.nih.gov/pubmed/36823429
http://dx.doi.org/10.1038/s41598-023-29046-5

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