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Ibrutinib facilitates the sensitivity of colorectal cancer cells to ferroptosis through BTK/NRF2 pathway

Ibrutinib is a drug that inhibits the protein Burton’s tyrosine kinase and thereby the nuclear translocation of Nrf2, which played a key role in mediating the activation of antioxidants during stress conditions and ferroptosis resistance. This study aimed to identify the effect of Ibrutinib and ferr...

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Detalles Bibliográficos
Autores principales:	Zhu, Jin-Feng, Liu, Yi, Li, Wen-Ting, Li, Ming-Hui, Zhen, Chao-Hui, Sun, Pei-Wei, Chen, Ji-Xin, Wu, Wen-Hao, Zeng, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2023
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950074/ https://www.ncbi.nlm.nih.gov/pubmed/36823108 http://dx.doi.org/10.1038/s41419-023-05664-9

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