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TNF-α contributes to sarcopenia through caspase-8/caspase-3/GSDME-mediated pyroptosis

Sarcopenia has become a leading cause of disability and mortality in the elderly. It has been reported that programmed cell death (PCD) is associated with the development of sarcopenia that is characterized by reduction of muscle fiber size and number. TNF-α is also validated to play a prominent rol...

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Detalles Bibliográficos
Autores principales: Wu, Jingying, Lin, Siming, Chen, Weixiao, Lian, Guili, Wu, Weibin, Chen, Ai, Sagor, Mohammad Ismail Hajary, Luo, Li, Wang, Huajun, Xie, Liangdi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950087/
https://www.ncbi.nlm.nih.gov/pubmed/36823174
http://dx.doi.org/10.1038/s41420-023-01365-6