Loss of pex5 sensitizes zebrafish to fasting due to deregulated mitochondria, mTOR, and autophagy

Animal models have been utilized to understand the pathogenesis of Zellweger spectrum disorders (ZSDs); however, the link between clinical manifestations and molecular pathways has not yet been clearly established. We generated peroxin 5 homozygous mutant zebrafish (pex5(−/−)) to gain insight into t...

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Detalles Bibliográficos
Autores principales: Bhandari, Sushil, Kim, Yong-Il, Nam, In-Koo, Hong, KwangHeum, Jo, Yunju, Yoo, Kyeong-Won, Liao, Weifang, Lim, Jae-Young, Kim, Seong-Jin, Um, Jae-Young, Kim, Peter K., Lee, Ho Sub, Ryu, Dongryeol, Kim, Seok-Hyung, Kwak, SeongAe, Park, Raekil, Choe, Seong-Kyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950184/
https://www.ncbi.nlm.nih.gov/pubmed/36821008
http://dx.doi.org/10.1007/s00018-023-04700-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950184/
https://www.ncbi.nlm.nih.gov/pubmed/36821008
http://dx.doi.org/10.1007/s00018-023-04700-3

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