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Loss of pex5 sensitizes zebrafish to fasting due to deregulated mitochondria, mTOR, and autophagy
Animal models have been utilized to understand the pathogenesis of Zellweger spectrum disorders (ZSDs); however, the link between clinical manifestations and molecular pathways has not yet been clearly established. We generated peroxin 5 homozygous mutant zebrafish (pex5(−/−)) to gain insight into t...
| Autores principales: | , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer International Publishing
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950184/ https://www.ncbi.nlm.nih.gov/pubmed/36821008 http://dx.doi.org/10.1007/s00018-023-04700-3 |