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Lenvatinib inhibits intrahepatic cholangiocarcinoma via Gadd45a-mediated cell cycle arrest

PURPOSE: To evaluate the anticancer activities of lenvatinib in ICC and its possible molecular mechanisms. METHODS: Patients-derived xenograft (PDX) model and cell line-derived xenograft (CDX) model were both used for the in vivo study. For in vivo work, ICC cell lines were applied to analyze the ef...

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Detalles Bibliográficos
Autores principales:	Yan, Xia, Wang, Dan, Ning, Zhouyu, Meng, Zhi-qiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2023
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950313/ https://www.ncbi.nlm.nih.gov/pubmed/36821012 http://dx.doi.org/10.1007/s12672-023-00631-4

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