High dose isoleucine stabilizes nuclear PTEN to suppress the proliferation of lung cancer

PURPOSE: Cancer cells require a supply of amino acids, particularly essential amino acids such as branched-chain amino acids (BCAAs, i.e., valine, leucine, and isoleucine), to meet the increased nutrient demands of malignant tumors. The cell-autonomous and non-autonomous roles of altered BCAA supply...

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Detalles Bibliográficos
Autores principales: Wang, Haiqing, Chen, Sen, Kang, Wenhui, Ding, Bojiao, Cui, Shulan, Zhou, Li, Zhang, Na, Luo, Huiying, Wang, Mingjuan, Zhang, Fan, Zhao, Zezhou, Guo, Zihu, Wang, Chao, Li, Liang, Wang, Zhengzhong, Chen, Xuetong, Wang, Yonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950318/
https://www.ncbi.nlm.nih.gov/pubmed/36820928
http://dx.doi.org/10.1007/s12672-023-00634-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950318/
https://www.ncbi.nlm.nih.gov/pubmed/36820928
http://dx.doi.org/10.1007/s12672-023-00634-1

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