Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening

The sporozoite stages of malaria parasites are the primary cause of infection of the vertebrate host and are targeted by (experimental) vaccines. Yet, little is known about their susceptibility to chemical intervention. Phenotypic high-throughput screens have not been feasible due to a lack of in vi...

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Detalles Bibliográficos
Autores principales: Miglianico, Marie, Bolscher, Judith M., Vos, Martijn W., Koolen, Karin J. M., de Bruijni, Marloes, Rajagopal, Deeya S., Chen, Emily, Kiczun, Michael, Gray, David, Campo, Brice, Sauerwein, Robert W., Dechering, Koen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950425/
https://www.ncbi.nlm.nih.gov/pubmed/36823266
http://dx.doi.org/10.1038/s42003-023-04599-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950425/
https://www.ncbi.nlm.nih.gov/pubmed/36823266
http://dx.doi.org/10.1038/s42003-023-04599-3

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