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Assessment of the drugability of initial malaria infection through miniaturized sporozoite assays and high-throughput screening
The sporozoite stages of malaria parasites are the primary cause of infection of the vertebrate host and are targeted by (experimental) vaccines. Yet, little is known about their susceptibility to chemical intervention. Phenotypic high-throughput screens have not been feasible due to a lack of in vi...
Autores principales: | Miglianico, Marie, Bolscher, Judith M., Vos, Martijn W., Koolen, Karin J. M., de Bruijni, Marloes, Rajagopal, Deeya S., Chen, Emily, Kiczun, Michael, Gray, David, Campo, Brice, Sauerwein, Robert W., Dechering, Koen J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950425/ https://www.ncbi.nlm.nih.gov/pubmed/36823266 http://dx.doi.org/10.1038/s42003-023-04599-3 |
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