Malaria-driven adaptation of MHC class I in wild bonobo populations

The malaria parasite Plasmodium falciparum causes substantial human mortality, primarily in equatorial Africa. Enriched in affected African populations, the B*53 variant of HLA-B, a cell surface protein that presents peptide antigens to cytotoxic lymphocytes, confers protection against severe malari...

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Detalles Bibliográficos
Autores principales: Wroblewski, Emily E., Guethlein, Lisbeth A., Anderson, Aaron G., Liu, Weimin, Li, Yingying, Heisel, Sara E., Connell, Andrew Jesse, Ndjango, Jean-Bosco N., Bertolani, Paco, Hart, John A., Hart, Terese B., Sanz, Crickette M., Morgan, David B., Peeters, Martine, Sharp, Paul M., Hahn, Beatrice H., Parham, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950436/
https://www.ncbi.nlm.nih.gov/pubmed/36823144
http://dx.doi.org/10.1038/s41467-023-36623-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950436/
https://www.ncbi.nlm.nih.gov/pubmed/36823144
http://dx.doi.org/10.1038/s41467-023-36623-9

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