MacroH2A histone variants modulate enhancer activity to repress oncogenic programs and cellular reprogramming

Considerable efforts have been made to characterize active enhancer elements, which can be annotated by accessible chromatin and H3 lysine 27 acetylation (H3K27ac). However, apart from poised enhancers that are observed in early stages of development and putative silencers, the functional significan...

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Detalles Bibliográficos
Autores principales: Mohammed Ismail, Wazim, Mazzone, Amelia, Ghiraldini, Flavia G., Kaur, Jagneet, Bains, Manvir, Munankarmy, Amik, Bagwell, Monique S., Safgren, Stephanie L., Moore-Weiss, John, Buciuc, Marina, Shimp, Lynzie, Leach, Kelsey A., Duarte, Luis F., Nagi, Chandandeep S., Carcamo, Saul, Chung, Chi-Yeh, Hasson, Dan, Dadgar, Neda, Zhong, Jian, Lee, Jeong-Heon, Couch, Fergus J., Revzin, Alexander, Ordog, Tamas, Bernstein, Emily, Gaspar-Maia, Alexandre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950461/
https://www.ncbi.nlm.nih.gov/pubmed/36823213
http://dx.doi.org/10.1038/s42003-023-04571-1

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