Age-Associated Upregulation of Glutamate Transporters and Glutamine Synthetase in Senescent Astrocytes In Vitro and in the Mouse and Human Hippocampus

Aging is marked by complex and progressive physiological changes, including in the glutamatergic system, that lead to a decline of brain function. Increased content of senescent cells in the brain, such as glial cells, has been reported to impact cognition both in animal models and human tissue duri...

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Detalles Bibliográficos
Autores principales: Matias, Isadora, Diniz, Luan Pereira, Araujo, Ana Paula Bergamo, Damico, Isabella Vivarini, de Moura, Pâmella, Cabral-Miranda, Felipe, Diniz, Fabiola, Parmeggiani, Belisa, de Mello Coelho, Valeria, Leite, Renata E. P., Suemoto, Claudia K., Ferreira, Gustavo Costa, Kubrusly, Regina Célia Cussa, Gomes, Flávia Carvalho Alcantara
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2023
Materias:
The Role of Glial Cells in the Nervous System in Health and Disease
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950616/
https://www.ncbi.nlm.nih.gov/pubmed/36815213
http://dx.doi.org/10.1177/17590914231157974

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