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Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation

INTRODUCTION: The antigen presentation molecule MHC class I related protein-1 (MR1) is best characterized by its ability to present bacterially derived metabolites of vitamin B2 biosynthesis to mucosal-associated invariant T-cells (MAIT cells). METHODS: Through in vitro human cytomegalovirus (HCMV)...

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Detalles Bibliográficos
Autores principales:	Ashley, Caroline L., McSharry, Brian P., McWilliam, Hamish E. G., Stanton, Richard J., Fielding, Ceri A., Mathias, Rommel A., Fairlie, David P., McCluskey, James, Villadangos, Jose A., Rossjohn, Jamie, Abendroth, Allison, Slobedman, Barry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950634/ https://www.ncbi.nlm.nih.gov/pubmed/36845106 http://dx.doi.org/10.3389/fimmu.2023.1107497

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