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Suppression of MR1 by human cytomegalovirus inhibits MAIT cell activation
INTRODUCTION: The antigen presentation molecule MHC class I related protein-1 (MR1) is best characterized by its ability to present bacterially derived metabolites of vitamin B2 biosynthesis to mucosal-associated invariant T-cells (MAIT cells). METHODS: Through in vitro human cytomegalovirus (HCMV)...
Autores principales: | Ashley, Caroline L., McSharry, Brian P., McWilliam, Hamish E. G., Stanton, Richard J., Fielding, Ceri A., Mathias, Rommel A., Fairlie, David P., McCluskey, James, Villadangos, Jose A., Rossjohn, Jamie, Abendroth, Allison, Slobedman, Barry |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950634/ https://www.ncbi.nlm.nih.gov/pubmed/36845106 http://dx.doi.org/10.3389/fimmu.2023.1107497 |
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