Cargando…

Berberine inhibits RA-FLS cell proliferation and adhesion by regulating RAS/MAPK/FOXO/HIF-1 signal pathway in the treatment of rheumatoid arthritis

AIMS: Rheumatoid arthritis (RA) is a common chronic immune disease. Berberine, as its main active ingredient, was also contained in a variety of medicinal plants such as Berberaceae, Buttercup, and Rutaceae, which are widely used in digestive system diseases in traditional Chinese medicine with anti...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Zhiqi, Chen, Meilin, Wang, Zhaoyi, Fan, Qiqi, Lin, Zili, Tao, Xiaoyu, Wu, Jiarui, Liu, Zhenquan, Lin, Ruichao, Zhao, Chongjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Editorial Society of Bone & Joint Surgery 2023
Materias:	Arthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950669/ https://www.ncbi.nlm.nih.gov/pubmed/36718649 http://dx.doi.org/10.1302/2046-3758.122.BJR-2022-0269.R1

Ejemplares similares

Berberine Modulates LPA Function to Inhibit the Proliferation and Inflammation of FLS-RA via p38/ERK MAPK Pathway Mediated by LPA(1)
por: Wang, Hui, et al.
Publicado: (2019)

From patients with arthralgia, pre-RA and recently diagnosed RA: what is the current status of understanding RA pathogenesis?
por: Molendijk, Marlieke, et al.
Publicado: (2018)

Infection rates in patients from five rheumatoid arthritis (RA) registries: contextualising an RA clinical trial programme
por: Yamanaka, Hisashi, et al.
Publicado: (2017)

Genetics of RA susceptibility, what comes next?
por: Ding, James, et al.
Publicado: (2015)

Joint involvement in RA starts predominantly in the hands: functional, clinical and imaging studies in clinically suspect arthralgia and during progression to RA
por: Khidir, Sarah J H, et al.
Publicado: (2023)

Lipidomics Indicates the Hepatotoxicity Effects of EtOAc Extract of Rhizoma Paridis
por: Li, Chaofeng, et al.
Publicado: (2022)

Time-varying risks of infection in patients as they proceed through the phases of ‘pre-RA’: results from the Scottish Early RA inception cohort
por: Porter, Duncan, et al.
Publicado: (2023)

Interplay between obesity and smoking with regard to RA risk
por: Hedström, Anna Karin, et al.
Publicado: (2019)

Hydroxychloroquine and the risk of respiratory infections among RA patients
por: Kremer, Joel M, et al.
Publicado: (2020)

Interplay between alcohol, smoking and HLA genes in RA aetiology
por: Hedström, Anna Karin, et al.
Publicado: (2019)

JAK inhibition and the holy grail for pain control in early RA
por: Pazmino, Sofia, et al.
Publicado: (2022)

PARP-1 inhibition attenuates the inflammatory response in the cartilage of a rat model of osteoarthritis
por: Liu, Zili, et al.
Publicado: (2021)

The interaction between polyphyllin I and SQLE protein induces hepatotoxicity through SREBP-2/HMGCR/SQLE/LSS pathway
por: Li, Zhiqi, et al.
Publicado: (2023)

Identifying flares in rheumatoid arthritis: reliability and construct validation of the OMERACT RA Flare Core Domain Set
por: Bykerk, Vivian P, et al.
Publicado: (2016)

Meniscus cell lysate induces mitochondrial dysfunction of fibroblast-like synoviocytes via upregulating ANT3 in osteoarthritis: aNT3 is a potentially important novel mediator and drug target in osteoarthritis
por: Du, Xue, et al.
Publicado: (2023)

Association of the IL2RA/CD25 Gene With Juvenile Idiopathic Arthritis
por: Hinks, Anne, et al.
Publicado: (2009)

Hand function is already reduced before RA development and reflects subclinical tenosynovitis
por: Krijbolder, Doortje Isabelle, et al.
Publicado: (2023)

Combined Metabolomics and Network Toxicology to Explore the Molecular Mechanism of Phytolacca acinose Roxb-Induced Hepatotoxicity in Zebrafish Larvae in Vivo
por: Cao, Dan, et al.
Publicado: (2021)

Identification of mechanics-responsive osteocyte signature in osteoarthritis subchondral bone
por: Zhou, Jun, et al.
Publicado: (2022)

Tapering and discontinuation of methotrexate in patients with RA treated with TNF inhibitors: data from the DREAM registry
por: Manders, Sofie H M, et al.
Publicado: (2015)

Fully automated joint space width measurement and digital X-ray radiogrammetry in early RA
por: Platten, Michael, et al.
Publicado: (2017)

Difficult-to-treat rheumatoid arthritis (D2T RA): clinical issues at early stages of disease
por: Leon, Leticia, et al.
Publicado: (2023)

Effects of alcohol consumption and smoking on risk for RA: results from a Swedish prospective cohort study
por: Hedenstierna, Louise, et al.
Publicado: (2021)

Association Between Genetic Variation in FOXO3 and Reductions in Inflammation and Disease Activity in Inflammatory Polyarthritis
por: Viatte, Sebastien, et al.
Publicado: (2016)

Anti-RA33 antibodies are present in a subset of patients with immune checkpoint inhibitor-induced inflammatory arthritis
por: Cappelli, Laura C, et al.
Publicado: (2022)

Pragmatic randomised controlled trial of very early etanercept and MTX versus MTX with delayed etanercept in RA: the VEDERA trial
por: Emery, Paul, et al.
Publicado: (2020)

Effectiveness of SARS-CoV-2 vaccination in patients with rheumatoid arthritis (RA) on DMARDs: as determined by antibody and T cell responses
por: Saleem, Benazir, et al.
Publicado: (2022)

Efficacy and drug persistence of baricitinib monotherapy is similar to combination therapy in patients with active RA: a prospective observational study
por: Bayat, Sara, et al.
Publicado: (2022)

Targeting type I interferon (IFN) signalling in patients with RA with a high type I IFN gene signature
por: Karonitsch, Thomas, et al.
Publicado: (2022)

Increased mortality in patients with RA-associated interstitial lung disease: data from a French administrative healthcare database
por: Juge, Pierre-Antoine, et al.
Publicado: (2023)

Value of imaging detected joint inflammation in explaining fatigue in RA at diagnosis and during the disease course: a large MRI study
por: Matthijssen, X M E, et al.
Publicado: (2021)

Effectiveness of electronic drug monitoring feedback to increase adherence in patients with RA initiating a biological DMARD: a randomised clinical trial
por: Hebing, Renske CF, et al.
Publicado: (2022)

Influence of disease activity on RA treatment choices in countries with restricted access to expensive, innovative drugs: a discrete choice experiment among rheumatologists
por: Hifinger, Monika, et al.
Publicado: (2017)

Postvaccination anti-S IgG levels predict anti-SARS-CoV-2 neutralising activity over 24 weeks in patients with RA
por: Schmiedeberg, Kristin, et al.
Publicado: (2022)

Crosstalk between FLS and chondrocytes is regulated by HIF-2α-mediated cytokines in arthritis
por: Huh, Yun Hyun, et al.
Publicado: (2015)

Ultrasound-detectable grey scale synovitis predicts future fulfilment of the 2010 ACR/EULAR RA classification criteria in patients with new-onset undifferentiated arthritis
por: Horton, Sarah C, et al.
Publicado: (2017)

Body mass index and treatment survival in patients with RA starting treatment with TNFα-inhibitors: long-term follow-up in the real-life METEOR registry
por: Bergstra, Sytske Anne, et al.
Publicado: (2020)

Moderate use of alcohol is associated with lower levels of C reactive protein but not with less severe joint inflammation: a cross-sectional study in early RA and healthy volunteers
por: Mangnus, Lukas, et al.
Publicado: (2018)

Short-term, intermediate-term and long-term risks of acute coronary syndrome in cohorts of patients with RA starting biologic DMARDs: results from four Nordic countries
por: Delcoigne, Benedicte, et al.
Publicado: (2022)

The role of accelerated growth plate fusion in the absence of SOCS2 on osteoarthritis vulnerability
por: Samvelyan, Hasmik Jasmine, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_rjrn7tb180fnprg616ldsl8qvc