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Incidental Detection of Pseudomembranous Colitis Through (18)F-FDG PET/CT During the Restaging of Colorectal Cancer

A 59-year-old man, previously submitted to anterior resection due to rectal cancer, underwent a contrast-enhanced computed tomography (ce-CT) for restaging before eventual chemotherapy. Because ce-CT showed a moderate enlargement of the descending colonic lumen, in despite the lack of symptoms, posi...

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Autor principal: Filippi, Luca
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950674/
https://www.ncbi.nlm.nih.gov/pubmed/36820009
http://dx.doi.org/10.4274/mirt.galenos.2022.94547
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author Filippi, Luca
author_facet Filippi, Luca
author_sort Filippi, Luca
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description A 59-year-old man, previously submitted to anterior resection due to rectal cancer, underwent a contrast-enhanced computed tomography (ce-CT) for restaging before eventual chemotherapy. Because ce-CT showed a moderate enlargement of the descending colonic lumen, in despite the lack of symptoms, positron emission tomography (PET)/CT (18)F-fluorodeoxyglucose (FDG) was carried out. (18)F-FDG PET/CT demonstrated highly increased tracer incorporation along the colon walls. Two days after the PET/CT examination, complaints of diarrhea and abdominal pain began. Clostridioides difficile stool test resulted positiv; thus, thus he started antibiotic therapy without benefit. Because follow-up ce-CT demonstrated a megacolon condition, he was submitted to hemicolectomy. Histology revealed a diffuse condition of pseudomembranous colitis (PMC). This case highlights the potential of (18)F-FDG PET/CT for detecting PMC morphological and functional features also in pre-symptomatic patients.
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spelling pubmed-99506742023-02-25 Incidental Detection of Pseudomembranous Colitis Through (18)F-FDG PET/CT During the Restaging of Colorectal Cancer Filippi, Luca Mol Imaging Radionucl Ther Interesting Image A 59-year-old man, previously submitted to anterior resection due to rectal cancer, underwent a contrast-enhanced computed tomography (ce-CT) for restaging before eventual chemotherapy. Because ce-CT showed a moderate enlargement of the descending colonic lumen, in despite the lack of symptoms, positron emission tomography (PET)/CT (18)F-fluorodeoxyglucose (FDG) was carried out. (18)F-FDG PET/CT demonstrated highly increased tracer incorporation along the colon walls. Two days after the PET/CT examination, complaints of diarrhea and abdominal pain began. Clostridioides difficile stool test resulted positiv; thus, thus he started antibiotic therapy without benefit. Because follow-up ce-CT demonstrated a megacolon condition, he was submitted to hemicolectomy. Histology revealed a diffuse condition of pseudomembranous colitis (PMC). This case highlights the potential of (18)F-FDG PET/CT for detecting PMC morphological and functional features also in pre-symptomatic patients. Galenos Publishing 2023-02 2023-02-23 /pmc/articles/PMC9950674/ /pubmed/36820009 http://dx.doi.org/10.4274/mirt.galenos.2022.94547 Text en ©Copyright 2023 by Turkish Society of Nuclear Medicine | Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Interesting Image
Filippi, Luca
Incidental Detection of Pseudomembranous Colitis Through (18)F-FDG PET/CT During the Restaging of Colorectal Cancer
title Incidental Detection of Pseudomembranous Colitis Through (18)F-FDG PET/CT During the Restaging of Colorectal Cancer
title_full Incidental Detection of Pseudomembranous Colitis Through (18)F-FDG PET/CT During the Restaging of Colorectal Cancer
title_fullStr Incidental Detection of Pseudomembranous Colitis Through (18)F-FDG PET/CT During the Restaging of Colorectal Cancer
title_full_unstemmed Incidental Detection of Pseudomembranous Colitis Through (18)F-FDG PET/CT During the Restaging of Colorectal Cancer
title_short Incidental Detection of Pseudomembranous Colitis Through (18)F-FDG PET/CT During the Restaging of Colorectal Cancer
title_sort incidental detection of pseudomembranous colitis through (18)f-fdg pet/ct during the restaging of colorectal cancer
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950674/
https://www.ncbi.nlm.nih.gov/pubmed/36820009
http://dx.doi.org/10.4274/mirt.galenos.2022.94547
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