(11)C-Methionine PET/CT and (18)F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma

A 70-year-old man with a tumor in the nasal and paranasal space, was pathologically diagnosed with an alveolar rhabdomyosarcoma, with right cervical lymph node metastasis. Magnetic resonance imaging revealed a primary tumor in the nasal and paranasal sinuses, with associated intracranial infiltratio...

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Autores principales: Hiroshima, Yuka, Otomi, Yoichi, Shinya, Takayoshi, Otsuka, Hideki, Harada, Masafumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2023
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950675/
https://www.ncbi.nlm.nih.gov/pubmed/36819829
http://dx.doi.org/10.4274/mirt.galenos.2022.96977
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author Hiroshima, Yuka
Otomi, Yoichi
Shinya, Takayoshi
Otsuka, Hideki
Harada, Masafumi
author_facet Hiroshima, Yuka
Otomi, Yoichi
Shinya, Takayoshi
Otsuka, Hideki
Harada, Masafumi
author_sort Hiroshima, Yuka
collection PubMed
description A 70-year-old man with a tumor in the nasal and paranasal space, was pathologically diagnosed with an alveolar rhabdomyosarcoma, with right cervical lymph node metastasis. Magnetic resonance imaging revealed a primary tumor in the nasal and paranasal sinuses, with associated intracranial infiltration. (11)C-methionine positron emission tomography/computed tomography (PET/CT) revealed increased uptake in the primary tumor and right cervical lymph node metastasis. (18)F-fluorodeoxyglucose PET/CT also revealed increased uptake in the primary tumor and right cervical lymph node. However, the physiological brain uptake overlapped with the primary tumor uptake. Our case suggests the usefulness of (11)C-methionine PET/CT for accurately assessing the extent of alveolar rhabdomyosarcoma, especially in cases with intracranial infiltration or those approximating the brain.
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spelling pubmed-99506752023-02-25 (11)C-Methionine PET/CT and (18)F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma Hiroshima, Yuka Otomi, Yoichi Shinya, Takayoshi Otsuka, Hideki Harada, Masafumi Mol Imaging Radionucl Ther Interesting Image A 70-year-old man with a tumor in the nasal and paranasal space, was pathologically diagnosed with an alveolar rhabdomyosarcoma, with right cervical lymph node metastasis. Magnetic resonance imaging revealed a primary tumor in the nasal and paranasal sinuses, with associated intracranial infiltration. (11)C-methionine positron emission tomography/computed tomography (PET/CT) revealed increased uptake in the primary tumor and right cervical lymph node metastasis. (18)F-fluorodeoxyglucose PET/CT also revealed increased uptake in the primary tumor and right cervical lymph node. However, the physiological brain uptake overlapped with the primary tumor uptake. Our case suggests the usefulness of (11)C-methionine PET/CT for accurately assessing the extent of alveolar rhabdomyosarcoma, especially in cases with intracranial infiltration or those approximating the brain. Galenos Publishing 2023-02 2023-02-23 /pmc/articles/PMC9950675/ /pubmed/36819829 http://dx.doi.org/10.4274/mirt.galenos.2022.96977 Text en ©Copyright 2023 by Turkish Society of Nuclear Medicine | Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Interesting Image
Hiroshima, Yuka
Otomi, Yoichi
Shinya, Takayoshi
Otsuka, Hideki
Harada, Masafumi
(11)C-Methionine PET/CT and (18)F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma
title (11)C-Methionine PET/CT and (18)F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma
title_full (11)C-Methionine PET/CT and (18)F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma
title_fullStr (11)C-Methionine PET/CT and (18)F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma
title_full_unstemmed (11)C-Methionine PET/CT and (18)F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma
title_short (11)C-Methionine PET/CT and (18)F-FDG PET/CT in the Evaluation of Adult Alveolar Rhabdomyosarcoma
title_sort (11)c-methionine pet/ct and (18)f-fdg pet/ct in the evaluation of adult alveolar rhabdomyosarcoma
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950675/
https://www.ncbi.nlm.nih.gov/pubmed/36819829
http://dx.doi.org/10.4274/mirt.galenos.2022.96977
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