Cargando…

High GNG4 predicts adverse prognosis for osteosarcoma: Bioinformatics prediction and experimental verification

BACKGROUND: Guanine nucleotide binding (G) protein subunit γ 4 (GNG4) is closely related to the malignant progression and poor prognosis of various tumours. However, its role and mechanism in osteosarcoma remain unclear. This study aimed to elucidate the biological role and prognostic value of GNG4...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Xiaohong, Tang, Fuxing, Zhang, Junlei, He, Mingwei, Xie, Tianyu, Tang, Haijun, Liu, Jianhong, Luo, Kai, Lu, Shenglin, Liu, Yun, Lu, Jili, He, Maolin, Wei, Qingjun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2023
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950737/ https://www.ncbi.nlm.nih.gov/pubmed/36845726 http://dx.doi.org/10.3389/fonc.2023.991483

Ejemplares similares

Significance of the neutrophil-to-lymphocyte ratio in predicting the response to neoadjuvant chemotherapy in extremity osteosarcoma: a multicentre retrospective study
por: Tang, Haijun, et al.
Publicado: (2022)

Identification and verification of a BMPs-related gene signature for osteosarcoma prognosis prediction
por: Xie, Long, et al.
Publicado: (2023)

Hypoxia-Induced miR-378a-3p Inhibits Osteosarcoma Invasion and Epithelial-to-Mesenchymal Transition via BYSL Regulation
por: Zhang, Junlei, et al.
Publicado: (2022)

Low GNG12 Expression Predicts Adverse Outcomes: A Potential Therapeutic Target for Osteosarcoma
por: Yuan, Jinghong, et al.
Publicado: (2021)

Construction of a transcription factor-miRNA-mRNA interactive network elucidates underlying pathogenesis for osteosarcoma and validation by qRT-PCR
por: Tang, Fuxing, et al.
Publicado: (2022)

A novel molecular signature for predicting prognosis and immunotherapy response in osteosarcoma based on tumor-infiltrating cell marker genes
por: Tang, Haijun, et al.
Publicado: (2023)

Trends of denosumab-related publications in web of science
por: Jiang, Xiaohong, et al.
Publicado: (2023)

Long non-coding RNA and circular RNA and coding RNA profiling of plasma exosomes of osteosarcoma by RNA seq
por: Liu, Yun, et al.
Publicado: (2023)

Differential expression and bioinformatics analysis of circRNA in osteosarcoma
por: Xi, Yizhe, et al.
Publicado: (2019)

Bioinformatics analysis of the key genes in osteosarcoma metastasis and immune invasion
por: Liang, Junqing, et al.
Publicado: (2022)

To Explore the Mechanism of the GRM4 Gene in Osteosarcoma by RNA Sequencing and Bioinformatics Approach
por: Pang, Yunguo, et al.
Publicado: (2018)

GNG7 and ADCY1 as diagnostic and prognostic biomarkers for pancreatic adenocarcinoma through bioinformatic-based analyses
por: Zhang, Youfu, et al.
Publicado: (2021)

ATG16L1 is a Potential Prognostic Biomarker and Immune Signature for Osteosarcoma: A Study Based on Bulk RNA and Single-Cell RNA-Sequencing
por: Qin, Zhaojie, et al.
Publicado: (2022)

Prediction and Identification of GPCRs Targeting for Drug Repurposing in Osteosarcoma
por: Tan, Manli, et al.
Publicado: (2022)

Prediction and verification of glycosyltransferase activity by bioinformatics analysis and protein engineering
por: Gerloff, Dietlind L., et al.
Publicado: (2022)

Validation the role of desmocollin-2 in osteosarcoma based on single cell and bulk RNA seq and experimental analyses
por: Zeng, Jiaxing, et al.
Publicado: (2023)

GNG12 as A Novel Molecular Marker for the Diagnosis and Treatment of Glioma
por: Liu, Runze, et al.
Publicado: (2022)

GNG5 is an unfavourable independent prognostic indicator of gliomas
por: Yang, Biao, et al.
Publicado: (2020)

GNG4 Promotes Tumor Progression in Colorectal Cancer
por: Liang, Liang, et al.
Publicado: (2021)

A new model of preoperative systemic inflammatory markers predicting overall survival of osteosarcoma: a multicenter retrospective study
por: Huang, Xianying, et al.
Publicado: (2022)

High expression of PSMC2 promotes gallbladder cancer through regulation of GNG4 and predicts poor prognosis
por: Zhu, Dawei, et al.
Publicado: (2021)

Identification of GNG7 as a novel biomarker and potential therapeutic target for gastric cancer via bioinformatic analysis and in vitro experiments
por: Duan, Houyu, et al.
Publicado: (2023)

Interaction gene set between osteoclasts and regulatory CD4(+) T cells can accurately predict the prognosis of patients with osteosarcoma
por: Li, Feicui, et al.
Publicado: (2023)

Five hypoxia and immunity related genes as potential biomarkers for the prognosis of osteosarcoma
por: Liu, Dachang, et al.
Publicado: (2022)

Bioinformatics prediction and experimental verification of key biomarkers for diabetic kidney disease based on transcriptome sequencing in mice
por: Zhao, Jing, et al.
Publicado: (2022)

Expression of NMU, PPBP and GNG4 in colon cancer and their influences on prognosis
por: Chen, Danyu, et al.
Publicado: (2022)

Identification of Candidate MicroRNA-mRNA Subnetwork for Predicting the Osteosarcoma Progression by Bioinformatics Analysis
por: Lu, Dejie, et al.
Publicado: (2022)

Bioinformatic prediction and experimental verification of Fur-regulated genes in the extreme acidophile Acidithiobacillus ferrooxidans
por: Quatrini, Raquel, et al.
Publicado: (2007)

GNG5 is a novel oncogene associated with cell migration, proliferation, and poor prognosis in glioma
por: Zhang, Wang, et al.
Publicado: (2021)

Development and Verification of a Hypoxic Gene Signature for Predicting Prognosis, Immune Microenvironment, and Chemosensitivity for Osteosarcoma
por: Wu, Fengfeng, et al.
Publicado: (2022)

The bioinformatic approach identifies PARM1 as a new potential prognostic factor in osteosarcoma
por: Feng, Haijun, et al.
Publicado: (2023)

High GNG4 expression is associated with poor prognosis in patients with lung adenocarcinoma
por: Zhou, Bodong, et al.
Publicado: (2021)

The Prognostic Value of GNG7 in Colorectal Cancer and Its Relationship With Immune Infiltration
por: Fang, Can, et al.
Publicado: (2022)

Identification of key genes as predictive biomarkers for osteosarcoma metastasis using translational bioinformatics
por: Ding, Fu-peng, et al.
Publicado: (2021)

Theoretical predictions and experimental verifications of SERS detection in colorants
por: Cao, Mingyan, et al.
Publicado: (2023)

LSINCT5 predicts unfavorable prognosis and exerts oncogenic function in osteosarcoma
por: He, Weidong, et al.
Publicado: (2019)

Bioinformatics prediction and experimental verification identify MAD2L1 and CCNB2 as diagnostic biomarkers of rhabdomyosarcoma
por: Xia, Tian, et al.
Publicado: (2021)

Bioinformatics prediction and experimental verification of a novel microRNA for myocardial fibrosis after myocardial infarction in rats
por: Guo, Qianqian, et al.
Publicado: (2023)

Osthole Inhibits Breast Cancer Progression through Upregulating Tumor Suppressor GNG7
por: Mei, Jie, et al.
Publicado: (2021)

Assessment of Significant Pathway Signaling and Prognostic Value of GNG11 in Ovarian Serous Cystadenocarcinoma
por: Jiang, Ming-Min, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2i5alvkebk5aif3n8rqqs6g6r7