Cargando…
Unaltered T cell responses to common antigens in individuals with Parkinson’s disease
BACKGROUND AND OBJECTIVES: Parkinson’s disease (PD) is associated with a heightened inflammatory state, including activated T cells. However, it is unclear whether these PD T cell responses are antigen specific or more indicative of generalized hyperresponsiveness. Our objective was to measure and c...
Autores principales: | Williams, Gregory P., Muskat, Kaylin, Frazier, April, Xu, Yaqian, Mateus, José, Grifoni, Alba, da Silva Antunes, Ricardo, Weiskopf, Daniela, Amara, Amy W., Standaert, David G., Goldman, Jennifer G., Litvan, Irene, Alcalay, Roy N., Sulzer, David, Lindestam Arlehamn, Cecilia S., Sette, Alessandro |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950758/ https://www.ncbi.nlm.nih.gov/pubmed/36495691 http://dx.doi.org/10.1016/j.jns.2022.120510 |
Ejemplares similares
-
Transcriptional analysis of peripheral memory T cells reveals Parkinson’s disease-specific gene signatures
por: Dhanwani, Rekha, et al.
Publicado: (2022) -
α-Synuclein-specific T cell reactivity is associated with preclinical and early Parkinson’s disease
por: Lindestam Arlehamn, Cecilia S., et al.
Publicado: (2020) -
Classical CD4 T cells as the cornerstone of antimycobacterial immunity
por: Morgan, Jeffrey, et al.
Publicado: (2021) -
The TCR repertoire of α-synuclein-specific T cells in Parkinson’s disease is surprisingly diverse
por: Singhania, Akul, et al.
Publicado: (2021) -
Autoimmunity in Parkinson's Disease: The Role of α-Synuclein-Specific T Cells
por: Garretti, Francesca, et al.
Publicado: (2019)