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Effectiveness of analgesic ear drops as add-on treatment to oral analgesics in children with acute otitis media: study protocol of the OPTIMA pragmatic randomised controlled trial
INTRODUCTION: Ear pain is the most prominent symptom of childhood acute otitis media (AOM). To control the pain and reduce reliance on antibiotics, evidence of effectiveness for alternative interventions is urgently needed. This trial aims to investigate whether analgesic ear drops added to usual ca...
Autores principales: | de Sévaux, Joline L H, Damoiseaux, Roger A M J, Hullegie, Saskia, Sanders, Elisabeth A M, de Wit, G Ardine, Zuithoff, Nicolaas P A, Yardley, Lucy, Anthierens, Sibyl, Little, Paul, Hay, Alastair D, Schilder, Anne G M, Venekamp, Roderick P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950909/ https://www.ncbi.nlm.nih.gov/pubmed/36813504 http://dx.doi.org/10.1136/bmjopen-2022-062071 |
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