Inducing primary brainstem gliomas in genetically engineered mice using RCAS/TVA retroviruses and Cre/loxP recombination

Genetically engineered mice are commonly used to model brainstem gliomas in pre-clinical research. One technique for inducing primary tumors in these genetically engineered mice involves delivering viral vectors containing the code for gene-editing proteins. We present a protocol for generating prim...

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Detalles Bibliográficos
Autores principales: Weidenhammer, Loren B., Liu, Harrison Q., Luo, Lixia, Williams, Nerissa T., Deland, Katherine, Kirsch, David G., Reitman, Zachary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Protocol
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950926/
https://www.ncbi.nlm.nih.gov/pubmed/36853662
http://dx.doi.org/10.1016/j.xpro.2023.102094

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