Effects of KMT2D mutation and its exon 39 mutation on the immune microenvironment and drug sensitivity in colorectal adenocarcinoma

BACKGROUND: KMT2D mutation (KMT2D(MT)) was found to play an important role in cancer immunity and response to immune checkpoint inhibitors (ICIs). The present study aims to investigate the association between KMT2D exon 39 mutation (K-ex39(MT)) and molecular and clinical characteristics in colorecta...

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Detalles Bibliográficos
Autores principales: Liu, Chuan, Jin, Yuzhi, Zhang, Hangyu, Yan, Junrong, Guo, Yixuan, Bao, Xuanwen, Zhao, Peng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2023
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950945/
https://www.ncbi.nlm.nih.gov/pubmed/36846668
http://dx.doi.org/10.1016/j.heliyon.2023.e13629

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950945/
https://www.ncbi.nlm.nih.gov/pubmed/36846668
http://dx.doi.org/10.1016/j.heliyon.2023.e13629

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