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Tivantinib alleviates inflammatory diseases by directly targeting NLRP3
NLRP3 inflammasome-mediated immune responses are involved in the pathogenesis of multiple inflammatory diseases, but few clinical drugs are identified that directly target the NLRP3 inflammasome to treat these diseases to date. Here, we show that the anticancer agent tivantinib is a selective inhibi...
Autores principales: | Huang, Yi, Guo, Yun, Zhou, Yan, Huang, Qian, Ru, Yi, Luo, Yingli, Xu, Wen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9950949/ https://www.ncbi.nlm.nih.gov/pubmed/36843841 http://dx.doi.org/10.1016/j.isci.2023.106062 |
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