Aberrant elevation of FTO levels promotes liver steatosis by decreasing the m(6)A methylation and increasing the stability of SREBF1 and ChREBP mRNAs

Previous studies have indicated an association of fat mass and obesity-associated (FTO) with nonalcoholic fatty liver disease (NAFLD), the most common chronic liver disease worldwide. This study aimed to decipher the complex role of FTO in hepatic lipid metabolism. We found that a decrease in N(6)-m...

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Detalles Bibliográficos
Autores principales: Tang, Zhili, Sun, Chao, Yan, Ying, Niu, Zhoumin, Li, Yuying, Xu, Xi, Zhang, Jing, Wu, Yuting, Li, Yan, Wang, Li, Hu, Cheng, Li, Zhuoyang, Jiang, Jingjing, Ying, Hao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951264/
https://www.ncbi.nlm.nih.gov/pubmed/36352530
http://dx.doi.org/10.1093/jmcb/mjac061

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