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Bicyclic Schellman Loop Mimics (BSMs): Rigid Synthetic C-Caps for Enforcing Peptide Helicity

[Image: see text] Macrocyclic peptides are the prevalent way to mimic interface helices for disruption of protein interactions, but current strategies to do this via synthetic C-cap mimics are underdeveloped and suboptimal. Bioinformatic studies described here were undertaken to better understand Sc...

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Detalles Bibliográficos
Autores principales: Mi, Tianxiong, Nguyen, Duyen, Burgess, Kevin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2023
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951308/
https://www.ncbi.nlm.nih.gov/pubmed/36844493
http://dx.doi.org/10.1021/acscentsci.2c01265

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