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Erythrocyte‐Inspired Functional Materials for Biomedical Applications

Erythrocytes are the most abundant cells in the blood. As the results of long‐term natural selection, their specific biconcave discoid morphology and cellular composition are responsible for gaining excellent biological performance. Inspired by the intrinsic features of erythrocytes, various artific...

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Autores principales: Luo, Zhiqiang, Sun, Lingyu, Bian, Feika, Wang, Yu, Yu, Yunru, Gu, Zhuxiao, Zhao, Yuanjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951328/
https://www.ncbi.nlm.nih.gov/pubmed/36581585
http://dx.doi.org/10.1002/advs.202206150
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author Luo, Zhiqiang
Sun, Lingyu
Bian, Feika
Wang, Yu
Yu, Yunru
Gu, Zhuxiao
Zhao, Yuanjin
author_facet Luo, Zhiqiang
Sun, Lingyu
Bian, Feika
Wang, Yu
Yu, Yunru
Gu, Zhuxiao
Zhao, Yuanjin
author_sort Luo, Zhiqiang
collection PubMed
description Erythrocytes are the most abundant cells in the blood. As the results of long‐term natural selection, their specific biconcave discoid morphology and cellular composition are responsible for gaining excellent biological performance. Inspired by the intrinsic features of erythrocytes, various artificial biomaterials emerge and find broad prospects in biomedical applications such as therapeutic delivery, bioimaging, and tissue engineering. Here, a comprehensive review from the fabrication to the applications of erythrocyte‐inspired functional materials is given. After summarizing the biomaterials mimicking the biological functions of erythrocytes, the synthesis strategies of particles with erythrocyte‐inspired morphologies are presented. The emphasis is on practical biomedical applications of these bioinspired functional materials. The perspectives for the future possibilities of the advanced erythrocyte‐inspired biomaterials are also discussed. It is hoped that the summary of existing studies can inspire researchers to develop novel biomaterials; thus, accelerating the progress of these biomaterials toward clinical biomedical applications.
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spelling pubmed-99513282023-02-25 Erythrocyte‐Inspired Functional Materials for Biomedical Applications Luo, Zhiqiang Sun, Lingyu Bian, Feika Wang, Yu Yu, Yunru Gu, Zhuxiao Zhao, Yuanjin Adv Sci (Weinh) Reviews Erythrocytes are the most abundant cells in the blood. As the results of long‐term natural selection, their specific biconcave discoid morphology and cellular composition are responsible for gaining excellent biological performance. Inspired by the intrinsic features of erythrocytes, various artificial biomaterials emerge and find broad prospects in biomedical applications such as therapeutic delivery, bioimaging, and tissue engineering. Here, a comprehensive review from the fabrication to the applications of erythrocyte‐inspired functional materials is given. After summarizing the biomaterials mimicking the biological functions of erythrocytes, the synthesis strategies of particles with erythrocyte‐inspired morphologies are presented. The emphasis is on practical biomedical applications of these bioinspired functional materials. The perspectives for the future possibilities of the advanced erythrocyte‐inspired biomaterials are also discussed. It is hoped that the summary of existing studies can inspire researchers to develop novel biomaterials; thus, accelerating the progress of these biomaterials toward clinical biomedical applications. John Wiley and Sons Inc. 2022-12-29 /pmc/articles/PMC9951328/ /pubmed/36581585 http://dx.doi.org/10.1002/advs.202206150 Text en © 2022 The Authors. Advanced Science published by Wiley‐VCH GmbH https://creativecommons.org/licenses/by/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Reviews
Luo, Zhiqiang
Sun, Lingyu
Bian, Feika
Wang, Yu
Yu, Yunru
Gu, Zhuxiao
Zhao, Yuanjin
Erythrocyte‐Inspired Functional Materials for Biomedical Applications
title Erythrocyte‐Inspired Functional Materials for Biomedical Applications
title_full Erythrocyte‐Inspired Functional Materials for Biomedical Applications
title_fullStr Erythrocyte‐Inspired Functional Materials for Biomedical Applications
title_full_unstemmed Erythrocyte‐Inspired Functional Materials for Biomedical Applications
title_short Erythrocyte‐Inspired Functional Materials for Biomedical Applications
title_sort erythrocyte‐inspired functional materials for biomedical applications
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951328/
https://www.ncbi.nlm.nih.gov/pubmed/36581585
http://dx.doi.org/10.1002/advs.202206150
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