Manipulation of PD‐L1 Endosomal Trafficking Promotes Anticancer Immunity

The aberrant regulation of PD‐L1 in tumor cells remains poorly understood. Here, the authors systematically investigate the endosomal trafficking of plasma membrane PD‐L1 in tumor cells. They show that plasma membrane PD‐L1 is continuously internalized, and then trafficked from early endosomes to mu...

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Detalles Bibliográficos
Autores principales: Ye, Zuodong, Xiong, Yiding, Peng, Wang, Wei, Wenjie, Huang, Lihong, Yue, Juliana, Zhang, Chunyuan, Lin, Ge, Huang, Feng, Zhang, Liang, Zheng, Songguo, Yue, Jianbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951344/
https://www.ncbi.nlm.nih.gov/pubmed/36567273
http://dx.doi.org/10.1002/advs.202206411

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