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Activation of the IL-17/TRAF6/NF-κB pathway is implicated in Aβ-induced neurotoxicity

BACKGROUND: Neuroinflammation plays a critical role in amyloid-β (Aβ) pathophysiology. The cytokine interleukin-17A (IL-17) is involved in the learning and memory process in the central nervous system, and its level was reported to be increased in Alzheimer's disease (AD) brains, while the effe...

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Detalles Bibliográficos
Autores principales: Liu, Yulan, Meng, Yang, Zhou, Chenliang, Yan, Juanjuan, Guo, Cuiping, Dong, Weiguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951515/
https://www.ncbi.nlm.nih.gov/pubmed/36823558
http://dx.doi.org/10.1186/s12868-023-00782-8