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Andrographolide Inhibits Static Mechanical Pressure-Induced Intervertebral Disc Degeneration via the MAPK/Nrf2/HO-1 Pathway

PURPOSE: To explore the molecular mechanism by which andrographolide (ADR) inhibits static mechanical pressure-induced apoptosis in nucleus pulposus cells (NPCs) and to assess the role of ADR in inhibiting IDD. METHODS: Hematoxylin-eosin (HE), toluidine blue, and immunofluorescence staining were use...

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Detalles Bibliográficos
Autores principales:	Zhang, Cunxin, Lu, Ziang, Lyu, Chaoliang, Zhang, Shanshan, Wang, Dechun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2023
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951603/ https://www.ncbi.nlm.nih.gov/pubmed/36845666 http://dx.doi.org/10.2147/DDDT.S392535

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