Sub-cellular sequestration of alkaline drugs in lysosomes: new insights for pharmaceutical development of lysosomal fluid

BACKGROUND AND PURPOSE: Lysosomal-targeted drug delivery can open a new strategy for drug therapy. However, there is currently no universally accepted simulated or artificial lysosomal fluid utilized in the pharmaceutical industry or recognized by the United States Pharmacopeia (USP). EXPERIMENTAL P...

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Detalles Bibliográficos
Autores principales: Yousef, Malaz, Le, Tyson S., Zuo, Jieyu, Park, Chulhun, Chacra, Nadia Bou, Davies, Neal M., Löbenberg, Raimar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9951787/
https://www.ncbi.nlm.nih.gov/pubmed/36846734
http://dx.doi.org/10.4103/1735-5362.363591

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