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Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study
Background: Fournier’s gangrene (FG) is a life-threatening, necrotizing infection. Due to the rareness of the disease, it is challenging to plan robust prospective studies. This study aims to describe current practice patterns of FG in Europe and identify implications for planning a prospective FG r...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952046/ https://www.ncbi.nlm.nih.gov/pubmed/36830108 http://dx.doi.org/10.3390/antibiotics12020197 |
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author | Schneidewind, Laila Kiss, Bernhard Stangl, Fabian P. Tandogdu, Zafer Wagenlehner, Florian M. E. Johansen, Truls E. Bjerklund Köves, Béla Medina-Polo, Jose Tapia, Ana Maria Kranz, Jennifer |
author_facet | Schneidewind, Laila Kiss, Bernhard Stangl, Fabian P. Tandogdu, Zafer Wagenlehner, Florian M. E. Johansen, Truls E. Bjerklund Köves, Béla Medina-Polo, Jose Tapia, Ana Maria Kranz, Jennifer |
author_sort | Schneidewind, Laila |
collection | PubMed |
description | Background: Fournier’s gangrene (FG) is a life-threatening, necrotizing infection. Due to the rareness of the disease, it is challenging to plan robust prospective studies. This study aims to describe current practice patterns of FG in Europe and identify implications for planning a prospective FG registry. Methods: Online non-validated 17-items survey among urologists treating FG in in European hospitals. Questionnaires were analyzed with LimeSurvey (LimeSurvey GmbH Hamburg, Germany). Results: 229 responses from ten different European countries were submitted, and 117 (51.1%) urologists completed the questionnaire. The departments treat a mean of 4.2 (SD 3.11) patients per year. The urology department mostly takes the lead in treating FG patients (n = 113; 96.6%). The practice in FG is very heterogenic and mostly case-based all over Europe, e.g., vacuum-assisted wound closure (VAC) is mostly used (n = 50; 42.7%) as adjunct wound. The biggest challenges in FG are the short time to diagnosis and treatment, standardization and establishment of guidelines, and disease awareness. Additionally, participants stated that an international registry is an outstanding initiative, and predictive models are needed. Conclusions: There is no standard of care in the diagnosis, treatment, and long-term care of FG all over Europe. Further research could be conducted with a prospective registry. |
format | Online Article Text |
id | pubmed-9952046 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99520462023-02-25 Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study Schneidewind, Laila Kiss, Bernhard Stangl, Fabian P. Tandogdu, Zafer Wagenlehner, Florian M. E. Johansen, Truls E. Bjerklund Köves, Béla Medina-Polo, Jose Tapia, Ana Maria Kranz, Jennifer Antibiotics (Basel) Article Background: Fournier’s gangrene (FG) is a life-threatening, necrotizing infection. Due to the rareness of the disease, it is challenging to plan robust prospective studies. This study aims to describe current practice patterns of FG in Europe and identify implications for planning a prospective FG registry. Methods: Online non-validated 17-items survey among urologists treating FG in in European hospitals. Questionnaires were analyzed with LimeSurvey (LimeSurvey GmbH Hamburg, Germany). Results: 229 responses from ten different European countries were submitted, and 117 (51.1%) urologists completed the questionnaire. The departments treat a mean of 4.2 (SD 3.11) patients per year. The urology department mostly takes the lead in treating FG patients (n = 113; 96.6%). The practice in FG is very heterogenic and mostly case-based all over Europe, e.g., vacuum-assisted wound closure (VAC) is mostly used (n = 50; 42.7%) as adjunct wound. The biggest challenges in FG are the short time to diagnosis and treatment, standardization and establishment of guidelines, and disease awareness. Additionally, participants stated that an international registry is an outstanding initiative, and predictive models are needed. Conclusions: There is no standard of care in the diagnosis, treatment, and long-term care of FG all over Europe. Further research could be conducted with a prospective registry. MDPI 2023-01-18 /pmc/articles/PMC9952046/ /pubmed/36830108 http://dx.doi.org/10.3390/antibiotics12020197 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Schneidewind, Laila Kiss, Bernhard Stangl, Fabian P. Tandogdu, Zafer Wagenlehner, Florian M. E. Johansen, Truls E. Bjerklund Köves, Béla Medina-Polo, Jose Tapia, Ana Maria Kranz, Jennifer Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study |
title | Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study |
title_full | Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study |
title_fullStr | Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study |
title_full_unstemmed | Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study |
title_short | Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study |
title_sort | practice patterns in fournier’s gangrene in europe and implications for a prospective registry study |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952046/ https://www.ncbi.nlm.nih.gov/pubmed/36830108 http://dx.doi.org/10.3390/antibiotics12020197 |
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