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Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study

Background: Fournier’s gangrene (FG) is a life-threatening, necrotizing infection. Due to the rareness of the disease, it is challenging to plan robust prospective studies. This study aims to describe current practice patterns of FG in Europe and identify implications for planning a prospective FG r...

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Autores principales: Schneidewind, Laila, Kiss, Bernhard, Stangl, Fabian P., Tandogdu, Zafer, Wagenlehner, Florian M. E., Johansen, Truls E. Bjerklund, Köves, Béla, Medina-Polo, Jose, Tapia, Ana Maria, Kranz, Jennifer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952046/
https://www.ncbi.nlm.nih.gov/pubmed/36830108
http://dx.doi.org/10.3390/antibiotics12020197
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author Schneidewind, Laila
Kiss, Bernhard
Stangl, Fabian P.
Tandogdu, Zafer
Wagenlehner, Florian M. E.
Johansen, Truls E. Bjerklund
Köves, Béla
Medina-Polo, Jose
Tapia, Ana Maria
Kranz, Jennifer
author_facet Schneidewind, Laila
Kiss, Bernhard
Stangl, Fabian P.
Tandogdu, Zafer
Wagenlehner, Florian M. E.
Johansen, Truls E. Bjerklund
Köves, Béla
Medina-Polo, Jose
Tapia, Ana Maria
Kranz, Jennifer
author_sort Schneidewind, Laila
collection PubMed
description Background: Fournier’s gangrene (FG) is a life-threatening, necrotizing infection. Due to the rareness of the disease, it is challenging to plan robust prospective studies. This study aims to describe current practice patterns of FG in Europe and identify implications for planning a prospective FG registry. Methods: Online non-validated 17-items survey among urologists treating FG in in European hospitals. Questionnaires were analyzed with LimeSurvey (LimeSurvey GmbH Hamburg, Germany). Results: 229 responses from ten different European countries were submitted, and 117 (51.1%) urologists completed the questionnaire. The departments treat a mean of 4.2 (SD 3.11) patients per year. The urology department mostly takes the lead in treating FG patients (n = 113; 96.6%). The practice in FG is very heterogenic and mostly case-based all over Europe, e.g., vacuum-assisted wound closure (VAC) is mostly used (n = 50; 42.7%) as adjunct wound. The biggest challenges in FG are the short time to diagnosis and treatment, standardization and establishment of guidelines, and disease awareness. Additionally, participants stated that an international registry is an outstanding initiative, and predictive models are needed. Conclusions: There is no standard of care in the diagnosis, treatment, and long-term care of FG all over Europe. Further research could be conducted with a prospective registry.
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spelling pubmed-99520462023-02-25 Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study Schneidewind, Laila Kiss, Bernhard Stangl, Fabian P. Tandogdu, Zafer Wagenlehner, Florian M. E. Johansen, Truls E. Bjerklund Köves, Béla Medina-Polo, Jose Tapia, Ana Maria Kranz, Jennifer Antibiotics (Basel) Article Background: Fournier’s gangrene (FG) is a life-threatening, necrotizing infection. Due to the rareness of the disease, it is challenging to plan robust prospective studies. This study aims to describe current practice patterns of FG in Europe and identify implications for planning a prospective FG registry. Methods: Online non-validated 17-items survey among urologists treating FG in in European hospitals. Questionnaires were analyzed with LimeSurvey (LimeSurvey GmbH Hamburg, Germany). Results: 229 responses from ten different European countries were submitted, and 117 (51.1%) urologists completed the questionnaire. The departments treat a mean of 4.2 (SD 3.11) patients per year. The urology department mostly takes the lead in treating FG patients (n = 113; 96.6%). The practice in FG is very heterogenic and mostly case-based all over Europe, e.g., vacuum-assisted wound closure (VAC) is mostly used (n = 50; 42.7%) as adjunct wound. The biggest challenges in FG are the short time to diagnosis and treatment, standardization and establishment of guidelines, and disease awareness. Additionally, participants stated that an international registry is an outstanding initiative, and predictive models are needed. Conclusions: There is no standard of care in the diagnosis, treatment, and long-term care of FG all over Europe. Further research could be conducted with a prospective registry. MDPI 2023-01-18 /pmc/articles/PMC9952046/ /pubmed/36830108 http://dx.doi.org/10.3390/antibiotics12020197 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Schneidewind, Laila
Kiss, Bernhard
Stangl, Fabian P.
Tandogdu, Zafer
Wagenlehner, Florian M. E.
Johansen, Truls E. Bjerklund
Köves, Béla
Medina-Polo, Jose
Tapia, Ana Maria
Kranz, Jennifer
Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study
title Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study
title_full Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study
title_fullStr Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study
title_full_unstemmed Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study
title_short Practice Patterns in Fournier’s Gangrene in Europe and Implications for a Prospective Registry Study
title_sort practice patterns in fournier’s gangrene in europe and implications for a prospective registry study
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952046/
https://www.ncbi.nlm.nih.gov/pubmed/36830108
http://dx.doi.org/10.3390/antibiotics12020197
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