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ABC Transporters and CYP3A4 Mediate Drug Interactions between Enrofloxacin and Salinomycin Leading to Increased Risk of Drug Residues and Resistance

Enrofloxacin (ENR) is one of the most common drugs used in poultry production to treat bacterial diseases, and there is a high risk of drug interactions (DDIs) between polyether anticoccidial drugs added to poultry feed over time. This may affect the efficacy of antibiotics or lead to toxicity, posi...

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Detalles Bibliográficos
Autores principales: Chen, Min, Yang, Yujuan, Ying, Yupeng, Huang, Jiamin, Sun, Mengyuan, Hong, Mian, Wang, Haizhen, Xie, Shuyu, Chen, Dongmei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952136/
https://www.ncbi.nlm.nih.gov/pubmed/36830313
http://dx.doi.org/10.3390/antibiotics12020403