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Deciphering Microbiota of Acute Upper Respiratory Infections: A Comparative Analysis of PCR and mNGS Methods for Lower Respiratory Trafficking Potential

HIGHLIGHTS: What are the main findings? Although there was a high concordance between methodologies, a hybridization-capture-based mNGS workflow was able to detect 29 additional upper respiratory microorganisms versus PCR. The identified microorganisms were rapidly characterized into three phenotypi...

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Detalles Bibliográficos
Autores principales: Almas, Sadia, Carpenter, Rob E., Singh, Anuradha, Rowan, Chase, Tamrakar, Vaibhav K., Sharma, Rahul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952210/
https://www.ncbi.nlm.nih.gov/pubmed/36825940
http://dx.doi.org/10.3390/arm91010006

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