Phosphorylation of the Human DNA Glycosylase NEIL2 Is Affected by Oxidative Stress and Modulates Its Activity

The DNA glycosylase NEIL2 plays a central role in maintaining genome integrity, in particular during oxidative stress, by recognizing oxidized base lesions and initiating repair of these via the base excision repair (BER) pathway. Post-translational modifications are important molecular switches tha...

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Detalles Bibliográficos
Autores principales: Myrup Holst, Camilla, Brøndum Andersen, Nanna, Thinggaard, Vibeke, Tilken, Mine, Lautrup, Sofie, Tesauro, Cinzia, Stevnsner, Tinna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952225/
https://www.ncbi.nlm.nih.gov/pubmed/36829914
http://dx.doi.org/10.3390/antiox12020355

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952225/
https://www.ncbi.nlm.nih.gov/pubmed/36829914
http://dx.doi.org/10.3390/antiox12020355

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