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Phosphorylation of the Human DNA Glycosylase NEIL2 Is Affected by Oxidative Stress and Modulates Its Activity
The DNA glycosylase NEIL2 plays a central role in maintaining genome integrity, in particular during oxidative stress, by recognizing oxidized base lesions and initiating repair of these via the base excision repair (BER) pathway. Post-translational modifications are important molecular switches tha...
Autores principales: | Myrup Holst, Camilla, Brøndum Andersen, Nanna, Thinggaard, Vibeke, Tilken, Mine, Lautrup, Sofie, Tesauro, Cinzia, Stevnsner, Tinna |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952225/ https://www.ncbi.nlm.nih.gov/pubmed/36829914 http://dx.doi.org/10.3390/antiox12020355 |
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