Cargando…

Polymeric Materials, Advances and Applications in Tissue Engineering: A Review

Tissue Engineering (TE) is an interdisciplinary field that encompasses materials science in combination with biological and engineering sciences. In recent years, an increase in the demand for therapeutic strategies for improving quality of life has necessitated innovative approaches to designing in...

Descripción completa

Detalles Bibliográficos
Autores principales: Socci, María Cecilia, Rodríguez, Gabriela, Oliva, Emilia, Fushimi, Shigeko, Takabatake, Kiyofumi, Nagatsuka, Hitoshi, Felice, Carmelo José, Rodríguez, Andrea Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952269/
https://www.ncbi.nlm.nih.gov/pubmed/36829712
http://dx.doi.org/10.3390/bioengineering10020218
_version_ 1784893588844314624
author Socci, María Cecilia
Rodríguez, Gabriela
Oliva, Emilia
Fushimi, Shigeko
Takabatake, Kiyofumi
Nagatsuka, Hitoshi
Felice, Carmelo José
Rodríguez, Andrea Paola
author_facet Socci, María Cecilia
Rodríguez, Gabriela
Oliva, Emilia
Fushimi, Shigeko
Takabatake, Kiyofumi
Nagatsuka, Hitoshi
Felice, Carmelo José
Rodríguez, Andrea Paola
author_sort Socci, María Cecilia
collection PubMed
description Tissue Engineering (TE) is an interdisciplinary field that encompasses materials science in combination with biological and engineering sciences. In recent years, an increase in the demand for therapeutic strategies for improving quality of life has necessitated innovative approaches to designing intelligent biomaterials aimed at the regeneration of tissues and organs. Polymeric porous scaffolds play a critical role in TE strategies for providing a favorable environment for tissue restoration and establishing the interaction of the biomaterial with cells and inducing substances. This article reviewed the various polymeric scaffold materials and their production techniques, as well as the basic elements and principles of TE. Several interesting strategies in eight main TE application areas of epithelial, bone, uterine, vascular, nerve, cartilaginous, cardiac, and urinary tissue were included with the aim of learning about current approaches in TE. Different polymer-based medical devices approved for use in clinical trials and a wide variety of polymeric biomaterials are currently available as commercial products. However, there still are obstacles that limit the clinical translation of TE implants for use wide in humans, and much research work is still needed in the field of regenerative medicine.
format Online
Article
Text
id pubmed-9952269
institution National Center for Biotechnology Information
language English
publishDate 2023
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-99522692023-02-25 Polymeric Materials, Advances and Applications in Tissue Engineering: A Review Socci, María Cecilia Rodríguez, Gabriela Oliva, Emilia Fushimi, Shigeko Takabatake, Kiyofumi Nagatsuka, Hitoshi Felice, Carmelo José Rodríguez, Andrea Paola Bioengineering (Basel) Review Tissue Engineering (TE) is an interdisciplinary field that encompasses materials science in combination with biological and engineering sciences. In recent years, an increase in the demand for therapeutic strategies for improving quality of life has necessitated innovative approaches to designing intelligent biomaterials aimed at the regeneration of tissues and organs. Polymeric porous scaffolds play a critical role in TE strategies for providing a favorable environment for tissue restoration and establishing the interaction of the biomaterial with cells and inducing substances. This article reviewed the various polymeric scaffold materials and their production techniques, as well as the basic elements and principles of TE. Several interesting strategies in eight main TE application areas of epithelial, bone, uterine, vascular, nerve, cartilaginous, cardiac, and urinary tissue were included with the aim of learning about current approaches in TE. Different polymer-based medical devices approved for use in clinical trials and a wide variety of polymeric biomaterials are currently available as commercial products. However, there still are obstacles that limit the clinical translation of TE implants for use wide in humans, and much research work is still needed in the field of regenerative medicine. MDPI 2023-02-06 /pmc/articles/PMC9952269/ /pubmed/36829712 http://dx.doi.org/10.3390/bioengineering10020218 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Socci, María Cecilia
Rodríguez, Gabriela
Oliva, Emilia
Fushimi, Shigeko
Takabatake, Kiyofumi
Nagatsuka, Hitoshi
Felice, Carmelo José
Rodríguez, Andrea Paola
Polymeric Materials, Advances and Applications in Tissue Engineering: A Review
title Polymeric Materials, Advances and Applications in Tissue Engineering: A Review
title_full Polymeric Materials, Advances and Applications in Tissue Engineering: A Review
title_fullStr Polymeric Materials, Advances and Applications in Tissue Engineering: A Review
title_full_unstemmed Polymeric Materials, Advances and Applications in Tissue Engineering: A Review
title_short Polymeric Materials, Advances and Applications in Tissue Engineering: A Review
title_sort polymeric materials, advances and applications in tissue engineering: a review
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952269/
https://www.ncbi.nlm.nih.gov/pubmed/36829712
http://dx.doi.org/10.3390/bioengineering10020218
work_keys_str_mv AT soccimariacecilia polymericmaterialsadvancesandapplicationsintissueengineeringareview
AT rodriguezgabriela polymericmaterialsadvancesandapplicationsintissueengineeringareview
AT olivaemilia polymericmaterialsadvancesandapplicationsintissueengineeringareview
AT fushimishigeko polymericmaterialsadvancesandapplicationsintissueengineeringareview
AT takabatakekiyofumi polymericmaterialsadvancesandapplicationsintissueengineeringareview
AT nagatsukahitoshi polymericmaterialsadvancesandapplicationsintissueengineeringareview
AT felicecarmelojose polymericmaterialsadvancesandapplicationsintissueengineeringareview
AT rodriguezandreapaola polymericmaterialsadvancesandapplicationsintissueengineeringareview