Cargando…
Polymeric Materials, Advances and Applications in Tissue Engineering: A Review
Tissue Engineering (TE) is an interdisciplinary field that encompasses materials science in combination with biological and engineering sciences. In recent years, an increase in the demand for therapeutic strategies for improving quality of life has necessitated innovative approaches to designing in...
Autores principales: | , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952269/ https://www.ncbi.nlm.nih.gov/pubmed/36829712 http://dx.doi.org/10.3390/bioengineering10020218 |
_version_ | 1784893588844314624 |
---|---|
author | Socci, María Cecilia Rodríguez, Gabriela Oliva, Emilia Fushimi, Shigeko Takabatake, Kiyofumi Nagatsuka, Hitoshi Felice, Carmelo José Rodríguez, Andrea Paola |
author_facet | Socci, María Cecilia Rodríguez, Gabriela Oliva, Emilia Fushimi, Shigeko Takabatake, Kiyofumi Nagatsuka, Hitoshi Felice, Carmelo José Rodríguez, Andrea Paola |
author_sort | Socci, María Cecilia |
collection | PubMed |
description | Tissue Engineering (TE) is an interdisciplinary field that encompasses materials science in combination with biological and engineering sciences. In recent years, an increase in the demand for therapeutic strategies for improving quality of life has necessitated innovative approaches to designing intelligent biomaterials aimed at the regeneration of tissues and organs. Polymeric porous scaffolds play a critical role in TE strategies for providing a favorable environment for tissue restoration and establishing the interaction of the biomaterial with cells and inducing substances. This article reviewed the various polymeric scaffold materials and their production techniques, as well as the basic elements and principles of TE. Several interesting strategies in eight main TE application areas of epithelial, bone, uterine, vascular, nerve, cartilaginous, cardiac, and urinary tissue were included with the aim of learning about current approaches in TE. Different polymer-based medical devices approved for use in clinical trials and a wide variety of polymeric biomaterials are currently available as commercial products. However, there still are obstacles that limit the clinical translation of TE implants for use wide in humans, and much research work is still needed in the field of regenerative medicine. |
format | Online Article Text |
id | pubmed-9952269 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2023 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-99522692023-02-25 Polymeric Materials, Advances and Applications in Tissue Engineering: A Review Socci, María Cecilia Rodríguez, Gabriela Oliva, Emilia Fushimi, Shigeko Takabatake, Kiyofumi Nagatsuka, Hitoshi Felice, Carmelo José Rodríguez, Andrea Paola Bioengineering (Basel) Review Tissue Engineering (TE) is an interdisciplinary field that encompasses materials science in combination with biological and engineering sciences. In recent years, an increase in the demand for therapeutic strategies for improving quality of life has necessitated innovative approaches to designing intelligent biomaterials aimed at the regeneration of tissues and organs. Polymeric porous scaffolds play a critical role in TE strategies for providing a favorable environment for tissue restoration and establishing the interaction of the biomaterial with cells and inducing substances. This article reviewed the various polymeric scaffold materials and their production techniques, as well as the basic elements and principles of TE. Several interesting strategies in eight main TE application areas of epithelial, bone, uterine, vascular, nerve, cartilaginous, cardiac, and urinary tissue were included with the aim of learning about current approaches in TE. Different polymer-based medical devices approved for use in clinical trials and a wide variety of polymeric biomaterials are currently available as commercial products. However, there still are obstacles that limit the clinical translation of TE implants for use wide in humans, and much research work is still needed in the field of regenerative medicine. MDPI 2023-02-06 /pmc/articles/PMC9952269/ /pubmed/36829712 http://dx.doi.org/10.3390/bioengineering10020218 Text en © 2023 by the authors. https://creativecommons.org/licenses/by/4.0/Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Review Socci, María Cecilia Rodríguez, Gabriela Oliva, Emilia Fushimi, Shigeko Takabatake, Kiyofumi Nagatsuka, Hitoshi Felice, Carmelo José Rodríguez, Andrea Paola Polymeric Materials, Advances and Applications in Tissue Engineering: A Review |
title | Polymeric Materials, Advances and Applications in Tissue Engineering: A Review |
title_full | Polymeric Materials, Advances and Applications in Tissue Engineering: A Review |
title_fullStr | Polymeric Materials, Advances and Applications in Tissue Engineering: A Review |
title_full_unstemmed | Polymeric Materials, Advances and Applications in Tissue Engineering: A Review |
title_short | Polymeric Materials, Advances and Applications in Tissue Engineering: A Review |
title_sort | polymeric materials, advances and applications in tissue engineering: a review |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9952269/ https://www.ncbi.nlm.nih.gov/pubmed/36829712 http://dx.doi.org/10.3390/bioengineering10020218 |
work_keys_str_mv | AT soccimariacecilia polymericmaterialsadvancesandapplicationsintissueengineeringareview AT rodriguezgabriela polymericmaterialsadvancesandapplicationsintissueengineeringareview AT olivaemilia polymericmaterialsadvancesandapplicationsintissueengineeringareview AT fushimishigeko polymericmaterialsadvancesandapplicationsintissueengineeringareview AT takabatakekiyofumi polymericmaterialsadvancesandapplicationsintissueengineeringareview AT nagatsukahitoshi polymericmaterialsadvancesandapplicationsintissueengineeringareview AT felicecarmelojose polymericmaterialsadvancesandapplicationsintissueengineeringareview AT rodriguezandreapaola polymericmaterialsadvancesandapplicationsintissueengineeringareview |